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SCOPOLAMINE-n-BUTYL BROMIDE (149-64-4)

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Table of contents:

Chemistry
Uses
Toxcity
Safety
Specification
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Chemistry

The MF of SCOPOLAMINE-n-BUTYL BROMIDE(149-64-4): C₂₁H₃₀BrNO₄
The MW of SCOPOLAMINE-n-BUTYL BROMIDE(149-64-4): 440.37
EINECS: 205-744-1
Melting point: 142-144 °C
solubility: H₂O: 50 mg/mL
form: powder
color: white
Appearance: Crystalline Solid
Stability: Stable at normal temperatures and pressures.
Incompatibilities: Strong oxidizing agents.
Decomposition: Carbon monoxide, Carbon dioxide, Nitrogen oxides.
Combustion Products: Fire may produce irritating, corrosive and/or toxic gases.
Synonyms: BUTYLMIN; HYOSCINE BUTYLBROMIDE; HYOSCINE N-BUTYL BROMIDE; SCOPOLAMINI BUTYLBROMIDUM; Scopolamine Butylbromide; N-butylhyoscinium bromide; hyoscine butylobromide; Hyoscine-N-Butyl Bromide
The Structure of SCOPOLAMINE-n-BUTYL BROMIDE(149-64-4):

Uses

SCOPOLAMINE-n-BUTYL BROMIDE(149-64-4) is anticholinergic and antispasmodic.

Toxicity Data With Reference

1.	orl-rat LD50:1040 mg/kg	AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. 180 (1969),155.
2.	scu-rat LD50:510 mg/kg	AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. 180 (1969),155.
3.	ivn-rat LD50:24 mg/kg	OYYAA2 Oyo Yakuri. Pharmacometrics. 23 (1982),461.
4.	idu-rat LD50:180 mg/kg	AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. 180 (1969),155.
5.	orl-mus LD50:1170 mg/kg	THERAP Therapie. 14 (1959),1096.
6.	ipr-mus LD50:73 mg/kg	JMCMAR Journal of Medicinal Chemistry. 16 (1973),1063.
7.	scu-mus LD50:304 mg/kg	NIIRDN “Drugs in Japan. Ethical Drugs, 6th Edition 1982” Edited by Japan Pharmaceutical Information Center. 6 (1982),354.
8.	ivn-mus LD50:10,300 µg/kg	OYYAA2 Oyo Yakuri. Pharmacometrics. 5 (1971),518.
9.	orl-gpg LD50:750 mg/kg	FRPSAX Farmaco, Edizione Scientifica. 39 (1984),3.
10.	scu-gpg LD50:65 mg/kg	FRPSAX Farmaco, Edizione Scientifica. 39 (1984),3.

Safety Profile

Poison by intravenous, subcutaneous, intraperitoneal, and intraduodenal routes. Moderately toxic by ingestion. Experimental reproductive effects. Used as an antispasmodic agent. When heated to decomposition it emits very toxic fumes of NO_x, NH₃, and Br⁻. See also BROMIDES and SCOPOLAMINE.
Hazard Codes:

Xn
Risk Statements: 22: Harmful if swallowed
WGK Germany: 3
RTECS: YM3500000

Specification

1. First Aid Measures:
Ingestion: If swallowed, wash out mouth with water provided person is conscious. Call a physician immediately.
Inhalation: If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
Skin: In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
Eyes: In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.
2. Storage: Keep tightly closed.

SCOPOLAMINE-n-BUTYL BROMIDE Basic information
Product Name:SCOPOLAMINE-n-BUTYL BROMIDE
CAS No:149-64-4
Formula:C₂₁H₃₀NO₄•Br

SCOPOLAMINE-n-BUTYL BROMIDE (149-64-4)

SCOPOLAMINE-n-BUTYL BROMIDE Basic information