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Name	Salicylhydroxamic acid	EINECS	201-934-3
CAS No.	89-73-6	Density	1.402g/cm3
PSA	69.56000	LogP	0.90210
Solubility	soluble	Melting Point		175 - 178 C
Formula	C7H7 N O3	Boiling Point	389.7°C at 760 mmHg
Molecular Weight	153.137	Flash Point	248.9oC
Transport Information	OTH	Appearance	brownish crystalline powder
Safety	Moderately toxic by intraperitoneal route. Mutation data reported. Used as a pharmaceutical and veterinary drug. When heated to decomposition it emits toxic fumes of NO_x.	Risk Codes	R40
Molecular Structure		Hazard Symbols
Synonyms	Salicylohydroxamicacid (6CI,7CI,8CI); 2-Hydroxybenzenehydroxamic acid; 2-Hydroxybenzohydroxamicacid; 2-Hydroxyphenylhydroxamic acid; N,2-Dihydroxybenzamide;N-Salicylhydroxamic acid; NSC 193440; NSC 5088; SHA; SHAM; Salicylhydroxamicacid; o-Hydroxybenzohydroxamic acid	Article Data	32

Salicylhydroxamic acid Chemical Properties

Molecular Formula: C₇H₇NO₃
Molar mass: 153.14 g/mol
EINECS: 201-934-3
Density: 1.402 g/cm³
Flash Point: 248.9 °C
Index of Refraction: 1.626
Boiling Point: 389.7 °C at 760 mmHg
Vapour Pressure: 9.01E-07 mmHg at 25°C
Melting point: 177 °C (dec.)(lit.)
Appearance: Off-white powder
Product categories of Salicylhydroxamic acid (89-73-6): Aromatic Hydrazides, Hydrazines, Hydrazones and Oximes;Hydroxylamines
Structure of Salicylhydroxamic acid (89-73-6):

XLogP3-AA: 0.9
H-Bond Donor: 3
H-Bond Acceptor: 3
Systematic Name: 2-Hydroxybenzenecarbohydroxamic acid
SMILES: O=C(c1ccccc1O)NO
InChI: InChI=1/C7H7NO3/c9-6-4-2-1-3-5(6)7(10)8-11/h1-4,9,11H,(H,8,10)
InChIKey: HBROZNQEVUILML-UHFFFAOYAX
Std. InChI: InChI=1S/C7H7NO3/c9-6-4-2-1-3-5(6)7(10)8-11/h1-4,9,11H,(H,8,10)
Std. InChIKey: HBROZNQEVUILML-UHFFFAOYSA-N

Salicylhydroxamic acid Uses

Salicylhydroxamic acid (89-73-6) can be used for pharmaceutical intermediate.It also can be used as hemical analysis reagents of bismuth, copper, nickel and copper.

Salicylhydroxamic acid Production

Salicylhydroxamic acid (89-73-6) cand be derived from the o-Hydroxybenzoate sodium hydroxide and Hydrochloric acid in the presence of Hydroxylamine condensation by acidification .

Salicylhydroxamic acid Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Source
mouse	LD50	intraperitoneal	860mg/kg (860mg/kg)	National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. Vol. JAN1986,
rat	LD50	intraperitoneal	600ug/kg (0.6mg/kg)	Toxicology Letters. Vol. (Suppl), Pg. 247, 1992.
rat	LD50	oral	5gm/kg (5000mg/kg)	Toxicology Letters. Vol. (Suppl), Pg. 247, 1992.

Salicylhydroxamic acid Consensus Reports

EPA Genetic Toxicology Program.

Salicylhydroxamic acid Safety Profile

Moderately toxic by intraperitoneal route. Mutation data reported. Used as a pharmaceutical and veterinary drug. When heated to decomposition it emits toxic fumes of NO_x.

Hazard Codes: Xn
Risk Statements:
20: Harmful by inhalation
21: Harmful in contact with skin
22: Harmful if swallowed
36: Irritating to the eyes
37: Irritating to the respiratory system
38: Irritating to the skin
40: Limited evidence of a carcinogenic effect
Safety Statements:
22: Do not breathe dust
24: Avoid contact with skin
25: Avoid contact with eyes
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36: Wear suitable protective clothing

Salicylhydroxamic acid Specification

Salicylhydroxamic acid (89-73-6) also can be called SHAM ; Salicylhydroxamate ; Saliaylhydroxamic acid ; 2-Hydroxybenzohydroxamic acid and Benzamide, N,2-dihydroxy- .

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