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Sodium methylarsonate

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Name

Sodium methylarsonate

EINECS 218-495-9
CAS No. 2163-80-6 Density 1.50 g/cm3
PSA 60.36000 LogP -0.59160
Solubility >=10 g/100 mL at 22 °C in water Melting Point 113-116 °C
Formula CH4AsNaO3 Boiling Point 393.3 °C at 760 mmHg
Molecular Weight 161.96 Flash Point 205.8 °C
Transport Information N/A Appearance odorless colorless solid
Safety 20/21-28-45-60-61 Risk Codes 22
Molecular Structure Molecular Structure of 2163-80-6 (Sodium methylarsonate) Hazard Symbols HarmfulXn
Synonyms

Methanearsonicacid, monosodium salt (8CI);Ansar 170;Ansar 170L;Ansar 529;Bueno 6;Daconate;Gepiron;MSMA;Monosodium acid methanearsonate;Monosodium acidmetharsonate;Monosodium methanearsonate;Monosodium methylarsonate;Sodiumacid methanearsonate;Weed 108;

 

Sodium methylarsonate Consensus Reports

Arsenic and its compounds are on the Community Right-To-Know List. EPA Genetic Toxicology Program.

Sodium methylarsonate Standards and Recommendations

OSHA PEL: TWA 0.5 mg(As)/m3
ACGIH TLV: BEI: 35 µ (As)/L inorganic arsenic and methylated metabolites in urine

Sodium methylarsonate Specification

The Monomethylarsonic acid, with the CAS registry number 2163-80-6, is also known as Methanearsonic acid monosodium salt. It belongs to the product categories of Alpha sort; ArsenicPesticides&Metabolites; Herbicides; H-MAlphabetic; M; METI - MZ; Pesticides&Metabolites. Its EINECS registry number is 218-495-9. This chemical's molecular formula is CH4AsNaO3 and molecular weight is 161.96. Its IUPAC name is called sodium hydroxy(methyl)arsinate. This chemical's classification codes are Agricultural Chemical; Herbicide; Mutation data; Organometallic; Skin / Eye Irritant. It is odorless colorless solid. When you are using this chemical, please be cautious about it as the following. This chemical may cause damage to health. It is harmful if swallowed.

Physical properties of Monomethylarsonic acid: (1)ACD/LogP: -1.75; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -3.39; (4)ACD/LogD (pH 7.4): -4.98; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 1; (8)ACD/KOC (pH 7.4): 1; (9)#H bond acceptors: 3; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 0; (12)Flash Point: 205.8 °C; (13)Enthalpy of Vaporization: 74.36 kJ/mol; (14)Melting Point: 113-116 °C; (15)Boiling Point: 393.3 °C at 760 mmHg; (16)Vapour Pressure: 8.17E-08 mmHg at 25°C.

You can still convert the following datas into molecular structure:
(1)Canonical SMILES: C[As](=O)(O)[O-].[Na+]
(2)InChI: InChI=1S/CH5AsO3.Na/c1-2(3,4)5;/h1H3,(H2,3,4,5);/q;+1/p-1
(3)InChIKey: JITOKQVGRJSHHA-UHFFFAOYSA-M

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cattle LD50 oral 230mg/kg (230mg/kg)   Bulletin of Environmental Contamination and Toxicology. Vol. 40, Pg. 119, 1988.
 
mammal (species unspecified) LD50 unreported 50mg/kg (50mg/kg)   "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 260, 1971.
mouse LD50 oral 300mg/kg (300mg/kg)   Bulletin of Environmental Contamination and Toxicology. Vol. 22, Pg. 143, 1979.
rabbit LC50 inhalation > 20gm/m3/4H (20000mg/m3)   Farm Chemicals Handbook. Vol. -, Pg. C52, 1991.
rabbit LD50 oral 102mg/kg (102mg/kg) BEHAVIORAL: MUSCLE WEAKNESS

GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

KIDNEY, URETER, AND BLADDER: URINE VOLUME DECREASED
Bulletin of Environmental Contamination and Toxicology. Vol. 40, Pg. 119, 1988.
rabbit LD50 skin 2500mg/kg (2500mg/kg)   Farm Chemicals Handbook. Vol. -, Pg. C211, 1991.
rat LC50 inhalation > 20gm/m3 (20000mg/m3)   Farm Chemicals Handbook. Vol. -, Pg. C211, 1991.
rat LD50 oral 700mg/kg (700mg/kg)   Farm Chemicals Handbook. Vol. -, Pg. C211, 1991.

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