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Sodium sulfadiazine

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Name

Sodium sulfadiazine

EINECS 208-919-0
CAS No. 547-32-0 Density
Solubility Melting Point
Formula C10H9N4NaO2S Boiling Point
Molecular Weight 272.26 Flash Point
Transport Information UN 3249 Appearance
Safety 22-26-36/37-45 Risk Codes 22-36/37/38-42/43
Molecular Structure Molecular Structure of 547-32-0 (Benzenesulfonamide,4-amino-N-2-pyrimidinyl-, sodium salt (1:1)) Hazard Symbols HarmfulXn
Synonyms

Benzenesulfonamide,4-amino-N-2-pyrimidinyl-, monosodium salt (9CI);Sodium, (N1-2-pyrimidinylsulfanilamido)-(7CI);Sulfadiazine, sodium deriv. (6CI);Sulfanilamide, N1-2-pyrimidinyl-,monosodium salt (8CI);2-Sulfanilamidopyrimidine sodium salt;Monosodium2-sulfanilamidopyrimidine;Sodium 2-sulfanilamidopyrimidine;Sodium sulfapyrimidine;Sulfadiazine sodium;Sulfapyrimidine sodium;

 

Sodium sulfadiazine Specification

This chemical is called Sulfadiazine Sodium, and its CAS registry number is 547-32-0. With the molecular formula of C10H9N4NaO2S, its classification codes are Antibacterial; Drug / Therapeutic Agent; Mutation data; Reproductive Effect. Additionally, it's used for cure sulfonamide, susceptible infections and it can also be used for T. gondii infection. However, it should be stored at 2-8°C.

Other characteristics of the Sulfadiazine Sodium can be summarised as followings: (1)#H bond acceptors: 6; (2)#H bond donors: 3; (3)#Freely Rotating Bonds: 2; (4)Polar Surface Area: 106.35 Å2.

When you are using this chemical, please be cautious about it as the following: This chemical is irritating to eyes, respiratory system and skin. It may cause sensitization by inhalation and skin contacting. You should wear suitable protective clothing if you use it. In case of contacting with eyes, rinse immediately with plenty of water and seek medical advice. 

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 1747mg/kg (1747mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 81, Pg. 17, 1944.
mouse LD50 intravenous 540mg/kg (540mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 94, Pg. 338, 1953.
mouse LD50 oral 1700mg/kg (1700mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 94, Pg. 338, 1953.
mouse LD50 subcutaneous 1408mg/kg (1408mg/kg)   Acta Medica Scandinavica, Supplement. Vol

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