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Basic information

  • Name:
  • Sucralose

  • CAS No.:
  • 56038-13-2

  • Molecular Structure:
  • Formula:
  • C12H19Cl3O8
  • Molecular Weight:
  • 397.64
  • Synonyms:
  • Trichlorosucrose;4,1,6-Trichloro-4,1,6-trideoxy-galacto-sucrose;1,6-Dichloro-1,6-dideoxy-beta-D-fructofuranosyl 4-chloro-4-deoxy-alpha-D-galactose;1,6-Dichloro-1,6-dideoxy-beta-D-fructofuranosyl 4-chloro-4-deoxy-alpha-D-galactopyranoside;See R-D-Galactopyranoside,1,6-dichloro-1,6- dideoxy-a-D-fructofuranosyl 4-chloro-4-deoxy-;Sucralose (Trichlorosucorose);Sucralose Fccv;Sucralose [BAN];(2R,3R,4R,5S,6R)-2-[(2R,3S,4S,5S)-2,5-bis(chloromethyl)-3,4-dihydroxy-oxolan-2-yl]oxy-5-chloro-6-(hydroxymethyl)oxane-3,4-diol;
  • EINECS:
  • 259-952-2
  • Density:
  • 1.69 g/cm3
  • Boiling Point:
  • 669.4 °C at 760 mmHg
  • Flash Point:
  • 358.7 °C
  • Appearance:
  • Off-White Amorphous Solid
  • Hazard Symbols:
  • IrritantXi
  • Risk Codes:
  • 36/37/38
  • Safety Description:
  • 26-37/39 Details

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Chemistry

IUPAC Name: (2R,3R,4R,5R,6R)-2-[(2R,3S,4S,5S)-2,5-Bis(Chloromethyl)-3,4-dihydroxyoxolan-2-yl]oxy-5-chloro-6-(hydroxymethyl)oxane-3,4-diol 
Synonyms: 1,6-Dichloro-1,6-dideoxy-beta-D-fructofuranosyl 4-chloro-4-deoxy-alpha-D-galactose ; Trichlorogalacto-sucrose ; 1',4,6'-Trichlorogalactosucrose
Molecular Formula: C12H19Cl3O8
Molecular Weight: 397.63 g/mol
Boiling point: 104-107 °C
Density: 1.375 g/cm3 
EINECS: 259-952-2 
Flash Point: 358.7 °C
Index of Refraction: 1.604 
Surface Tension: 76.5 dyne/cm
Enthalpy of Vaporization: 112.59 kJ/mol
Boiling Point: 669.4 °C at 760 mmHg
Vapour Pressure: 8.79E-21 mmHg at 25 °C
Following is the structure of Sucralose (CAS NO.56038-13-2):
     
Canonical SMILES: C(C1C(C(C(C(O1)OC2(C(C(C(O2)CCl)O)O)CCl)O)O)Cl)O
Isomeric SMILES: C([C@@H]1[C@@H]([C@@H]([C@H]([C@H](O1)O[C@]2([C@H]([C@@H]([C@H](O2)CCl)
O)O)CCl)O)O)Cl)O
InChI: InChI=1S/C12H19Cl3O8/c13-1-4-7(17)10(20)12(3-14,22-4)23-11-9(19)8(18)6(15)5(2-16)21-11/h4-11,16-20H,1-3H2/t4-,5-,6+,7-,8+,9-,10+,11-,12+/m1/s1
InChIKey: BAQAVOSOZGMPRM-QBMZZYIRSA-N

History

 Sucralose (CAS NO.56038-13-2) was discovered by scientists from Tate & Lyle in 1976,working with researchers Leslie Hough and Shashikant Phadnis at Queen Elizabeth College.On a late-summer day, Phadnis was told to test the powder. Phadnis thought that Hough asked him to taste it, and he did this.Then he found the compound to be exceptionally sweet (the final formula was 600 times as sweet as sugar).

Uses

 Sucralose (CAS NO.56038-13-2) is used as sweetner of zero-calorie sugar. It also can be used in baking or in products that require a longer shelf life.

Safety Profile

Hazard Codes:  IrritantXi
Risk Statements:  36/37/38 
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements:  26-37/39 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S37/39:Wear suitable gloves and eye/face protection.
RTECS: LW5440140

Specification

 Sucralose (CAS NO.56038-13-2) is a zero-calorie sugar substitute artificial sweetener. Sucralose is approximately 600 times as sweet as sucrose (table sugar), it is stable under heat and over a broad range of pH conditions. So it can be used in baking or in products that require a longer shelf life. Sucralose is typically added to foods in very small quantities. The classification code of Sucralose (CAS NO.56038-13-2) are flavoring agents, food additives, sweetening agents.

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