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Basic information

  • Name:
  • Tannic acid

  • CAS No.:
  • 1401-55-4

  • Formula:
  • C76H52O46
  • Synonyms:
  • Bondtite 345;Brewtan C;Colatan GT 100;F-Tannin;FS 500M;Floctan 3;Gallotannic acid;Hifix SL;Hifix SW-A;Sunlife TN;
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Chemistry

Molecular structure of Tannic acid (CAS NO.1401-55-4) is:

Product Name: Tannic acid
CAS Registry Number: 1401-55-4
Molecular Weight: 1701.19848 [g/mol]
Molecular Formula: C76H52O46
XLogP3-AA: 6.2
H-Bond Donor: 25
H-Bond Acceptor: 46 
EINECS: 215-753-2
Melting Point: 218 °C(lit.)
Surface Tension: 203.1 dyne/cm
Density: 2.12 g/cm3 
Flash Point: 198 °C
Water Solubility: 250 g/L (20 °C)
Sensitive: Air & Light Sensitive
Stability: Stable. Incompatible with metallic salts, strong oxidizing agents, iron and other heavy metals. 
Product Categories: Catechins & Tannins

Uses

 Tannic acid (CAS NO.1401-55-4) is mainly used for tanning, also used in medicine, ink, printing, rubber and metallurgy industries and water treatment, etc.

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
domestic animals - goat/sheep LDLo intraperitoneal 1gm/kg (1000mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: FOOD INTAKE (ANIMAL)

LIVER: "JAUNDICE, OTHER OR UNCLASSIFIED"
Research in Veterinary Science. Vol. 53, Pg. 280, 1992.
domestic animals - goat/sheep LDLo oral 1gm/kg (1000mg/kg) GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH

LIVER: "HEPATITIS (HEPATOCELLULAR NECROSIS), ZONAL"

KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)"
Veterinary and Human Toxicology. Vol. 37, Pg. 50, 1995.
guinea pig LDLo intravenous 40mg/kg (40mg/kg)   "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 571, 1969.
mouse LD50 intramuscular 120mg/kg (120mg/kg)   Journal of Pharmacy and Pharmacology. Vol. 9, Pg. 98, 1957.
mouse LD50 intramuscular 350mg/kg (350mg/kg)   Journal of Pharmacy and Pharmacology. Vol. 9, Pg. 98, 1957.
mouse LD50 intramuscular > 1600mg/kg (1600mg/kg)   Journal of Pharmacy and Pharmacology. Vol. 9, Pg. 98, 1957.
mouse LD50 intramuscular > 1600mg/kg (1600mg/kg)   Journal of Pharmacy and Pharmacology. Vol. 9, Pg. 98, 1957.
mouse LD50 intraperitoneal 120mg/kg (120mg/kg)   Planta Medica. Vol. 52, Pg. 272, 1986.
mouse LD50 intraperitoneal 150mg/kg (150mg/kg)   Journal of Pharmacy and Pharmacology. Vol. 9, Pg. 98, 1957.
mouse LD50 intraperitoneal 320mg/kg (320mg/kg)   Journal of Pharmacy and Pharmacology. Vol. 9, Pg. 98, 1957.
mouse LD50 intraperitoneal 360mg/kg (360mg/kg)   Journal of Pharmacy and Pharmacology. Vol. 9, Pg. 98, 1957.
mouse LD50 intravenous 50mg/kg (50mg/kg)   Journal of Pharmacy and Pharmacology. Vol. 9, Pg. 98, 1957.
mouse LD50 intravenous 130mg/kg (130mg/kg)   Journal of Pharmacy and Pharmacology. Vol. 9, Pg. 98, 1957.
mouse LD50 intravenous 130mg/kg (130mg/kg)   Journal of Pharmacy and Pharmacology. Vol. 9, Pg. 98, 1957.
mouse LD50 subcutaneous 140mg/kg (140mg/kg)   Journal of Pharmacy and Pharmacology. Vol. 9, Pg. 98, 1957.
mouse LD50 subcutaneous > 1600mg/kg (1600mg/kg)   Journal of Pharmacy and Pharmacology. Vol. 9, Pg. 98, 1957.
mouse LD50 subcutaneous > 1600mg/kg (1600mg/kg)   Journal of Pharmacy and Pharmacology. Vol. 9, Pg. 98, 1957.
mouse LDLo intravenous 10mg/kg (10mg/kg) SENSE ORGANS AND SPECIAL SENSES: HEMORRHAGE: EYE

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Journal of Pharmacology and Experimental Therapeutics. Vol. 77, Pg. 63, 1943.
mouse LDLo oral 2gm/kg (2000mg/kg) SENSE ORGANS AND SPECIAL SENSES: HEMORRHAGE: EYE

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Journal of Pharmacology and Experimental Therapeutics. Vol. 77, Pg. 63, 1943.
mouse LDLo subcutaneous 75mg/kg (75mg/kg) SENSE ORGANS AND SPECIAL SENSES: HEMORRHAGE: EYE

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Journal of Pharmacology and Experimental Therapeutics. Vol. 77, Pg. 63, 1943.
rabbit LD50 oral 5gm/kg (5000mg/kg) GASTROINTESTINAL: GASTRITIS

LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA
American Journal of Veterinary Research. Vol. 23, Pg. 1264, 1962.
rat LD50 oral 2260mg/kg (2260mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD

LUNGS, THORAX, OR RESPIRATION: DYSPNEA

GASTROINTESTINAL: OTHER CHANGES
"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 571, 1969.
rat LDLo parenteral 1400mg/kg (1400mg/kg)   Food and Cosmetics Toxicology. Vol. 14, Pg. 565, 1976.
rat LDLo subcutaneous 200mg/kg (200mg/kg)   Wiener Klinische Wochenschrift. Vol. 62, Pg. 270, 1950.

Safety Profile

Hazard Codes: IrritantXi,Xn
Risk Statements: 40-62-63-68-36/37/38 
R40:Limited evidence of a carcinogenic effect. 
R62:Risk of impaired fertility. 
R63:Possible risk of harm to the unborn child. 
R68:Possible risk of irreversible effects. 
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 24/25-36-26-36/37/39-22 
S24/25:Avoid contact with skin and eyes. 
S36:Wear suitable protective clothing. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection. 
S22:Do not breathe dust.
WGK Germany: 2
RTECS: WW5075000
HS Code: 32019090

Specification

 Tannic acid , its cas register number is 1401-55-4. It also can be called Gallotannic acid ; Gallotannin ; Galloylglucose ; Glycerite ; Quebracho ; Tannins .It is a light yellow to tan solid with a faint odor.It sinks and mixes with water.

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