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Taurocholic acid

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Taurocholic acid

EINECS 201-336-2
CAS No. 81-24-3 Density
Solubility Melting Point 1.264 g/cm3
Formula C26H45 N O7 S Boiling Point
Molecular Weight 515.78 Flash Point
Transport Information Appearance
Safety Moderately toxic by intraperitoneal route. An emulsifying agent used as a food additive. When heated to decomposition it emits very toxic fumes of NOx and SOx. Risk Codes
Molecular Structure Molecular Structure of 81-24-3 (Ethanesulfonic acid,2-[[(3a,5b,7a,12a)-3,7,12-trihydroxy-24-oxocholan-24-yl]amino]-) Hazard Symbols
Synonyms

Taurine,N-choloyl- (8CI); Cholane, ethanesulfonic acid deriv.; 3a,7a,12a-Trihydroxy-5b-cholanic acid-24-taurine; Cholaic acid; Cholic acid taurine conjugate;Cholyltaurine; N-Choloyltaurine; NSC 25505; Taurocholic acid

 

Taurocholic acid Chemical Properties

Product Name: Taurocholic acid
The MF of Taurocholic acid (CAS NO.81-24-3) is C26H45NO7S.

      
The MW of Taurocholic acid (CAS NO.81-24-3) is 515.7.
Synonyms of Taurocholic acid (CAS NO.81-24-3): 2-[(3a,7a,12a-Trihydroxy-24-oxo-5b-cholan-24-yl)amino]ethanesulfonic acid ; Ethanesulfonic acid, 2-(((3alpha,5beta,7alpha,12alpha)-3,7,12-trihydroxy-24-oxocholan-24-yl)amino)- 
Product Categories: Miscellaneous Natural Products
Apperance: deliquescent yellowish crystalline bile acid
Index of Refraction: 1.565
Melting Point: 125.0 °C 
Density: 1.264 g/ml
EINECS: 201-336-2

Taurocholic acid Uses

In medical use, Taurocholic acid (CAS NO.81-24-3) is administered as a cholagogue and choleretic.For commercial use, taurocholic acid is manufactured from cattle bile, a byproduct of the meat-processing industry.This acid is also one of the many molecules in the body that has cholesterol as its precursor.

Taurocholic acid Production

Extracted from animal organs

Taurocholic acid Toxicity Data With Reference

1.    

ipr-rat LD50:450 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 24 (1973),37.
2.    

ipr-mus LD50:620 mg/kg

    TXAPA9    Toxicology and Applied Pharmacology. 24 (1973),37.

Taurocholic acid Safety Profile

Moderately toxic by intraperitoneal route. An emulsifying agent used as a food additive. When heated to decomposition it emits very toxic fumes of NOx and SOx.

Taurocholic acid Specification

 Taurocholic acid, known also as cholaic acid, cholyltaurine, or acidum cholatauricum, is a deliquescent yellowish crystalline bile acid involved in the emulsification of fats. It occurs as a sodium salt in the bile of mammals. It is a conjugate of cholic acid with taurine.

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