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Cas Database |
| Name |
Thioproperazine |
EINECS | 206-262-4 |
| CAS No. | 316-81-4 | Density | 1.237g/cm3 |
| PSA | 80.78000 | LogP | 4.19870 |
| Solubility | N/A | Melting Point |
140ºC |
| Formula | C22H30 N4 O2 S2 | Boiling Point | 612.2°Cat760mmHg |
| Molecular Weight | 446.638 | Flash Point | 324°C |
| Transport Information | N/A | Appearance | N/A |
| Safety | Moderately toxic by ingestion. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of SOx and NOx. | Risk Codes | N/A |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
Phenothiazine-2-sulfonamide,N,N-dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]- (6CI,8CI); 7843RP;Cephalmin;N,N-Dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]-2-phenothiazinesulfonamide;RP 7843; SKF 5883; Sulfenazin; Thioperazine; Thioproperazine; Tioproperazin |
Article Data | 4 |
Thioproperazine Chemical Properties
IUPAC Name: N,N-Dimethyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine-2-sulfonamide
The MF of Thioperazine (CAS NO.316-81-4) is C22H30N4O2S2.
The MW of Thioperazine (CAS NO.316-81-4) is 446.63.
Synonyms of Thioperazine (CAS NO.316-81-4): N,N-Dimethyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine-2-sulfonamide ; 10H-Phenothiazine-2-sulfonamide, N,N-dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]- ; Cephalmin;Phenothiazine-2-sulfonamide, N,N-dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]- ; Sulfenazin
Solubility in water: 3.6 mg/L (25 °C)
Index of Refraction: 1.615
EINECS: 206-262-4
Density: 1.237 g/ml
Flash Point: 324 °C
Boiling Point: 612.2 °C
Melting Point: 140 °C
Thioproperazine Uses
Thioperazine (CAS NO.316-81-4) is used in medicine, pesticide manufacturing.
Thioproperazine Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 130mg/kg (130mg/kg) | Psychopharmacology Service Center, Bulletin. Vol. 2, Pg. 17, 1963. | |
| mouse | LD50 | intravenous | 70mg/kg (70mg/kg) | Psychopharmacology Service Center, Bulletin. Vol. 2, Pg. 17, 1963. | |
| mouse | LD50 | oral | 830mg/kg (830mg/kg) | BEHAVIORAL: ANTIPSYCHOTIC | Developments in Neuroscience Vol. 7, Pg. 45, 1980. |
| mouse | LD50 | subcutaneous | 500mg/kg (500mg/kg) | Psychopharmacology Service Center, Bulletin. Vol. 2, Pg. 17, 1963. | |
| rat | LD50 | intravenous | 25mg/kg (25mg/kg) | Therapie. Vol. 18, Pg. 373, 1963. |
Thioproperazine Safety Profile
Moderately toxic by ingestion. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of SOx and NOx.
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