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Cas Database

Name	Thioridazine	EINECS	200-044-2
CAS No.	50-52-2	Density	1.237 g/cm³
PSA	57.08000	LogP	5.88850
Solubility	1.113mg/L(22.5 oC)	Melting Point	72-74°
Formula	C₂₁H₂₆N₂S₂	Boiling Point	515.665 °C at 760 mmHg
Molecular Weight	370.583	Flash Point	265.665 °C
Transport Information	N/A	Appearance	N/A
Safety	16-36/37-45-61	Risk Codes	11-23/24/25-39/23/24/25-52/53
Molecular Structure		Hazard Symbols	F,T
Synonyms	Phenothiazine,10-[2-(1-methyl-2-piperidyl)ethyl]-2-(methylthio)- (6CI,8CI);10-[2-(1-Methyl-2-piperidyl)ethyl]-2-(methylthio)phenothiazine;2-Methylmercapto-10-[2-N-methyl-2-piperidyl)ethyl]phenothiazine;Sonapax;Thioridazine prolongatum;dl-Thioridazine;	Article Data	12

Thioridazine Chemical Properties

Chemical Name: Thioridazine
IUPAC NAME: 10-[2-(1-Methylpiperidin-2-yl)ethyl]-2-methylsulfanylphenothiazine
CAS No.: 50-52-2
EINECS: 200-044-2
Molecular Formula: C₂₁H₂₆N₂S₂
Molecular Weight: 370.57 g/mol
Density: 1.23 g/cm³
Flash Point: 265.7 °C
Boiling Point: 515.7 °C at 760 mmHg
Following is the structure of 10-(2-(1-Methyl-2-piperidyl)ethyl)-2-(methylthio)phenothiazine (50-52-2):

Product Categories about 10-(2-(1-Methyl-2-piperidyl)ethyl)-2-(methylthio)phenothiazine (50-52-2) is mainly refer to Thioridazine
The chemical synonymous of 10-(2-(1-Methyl-2-piperidyl)ethyl)-2-(methylthio)phenothiazine (50-52-2) are Thioridazine;10-((1-Methyl-2-piperidyl)ethyl)-2-(methylthio)-phenothiazin;10-(2-(1-Methyl-2-piperidinyl)ethyl)-2-(methylthio)-10H-phenothiazin;10-(2-(1-Methyl-2-piperidyl)ethyl)-2-(methylthio)phenothiazine;10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylsulfanyl)-10H-phenothiazine;10h-Phenothiazine, 10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylthio)-

Thioridazine Toxicity Data With Reference

1.	sln-dmg-orl 100 mg/L	IJEBA6 Indian Journal of Experimental Biology. 11 (1973),403.
2.	orl-cld TDLo:28 mg/kg/2W-I	AJPSAO American Journal of Psychiatry. 143 (1985),1176.
3.	orl-cld TDLo:28 mg/kg/2W-I:BAH	AJPSAO American Journal of Psychiatry. 143 (1985),1176.
4.	orl-wmn TDLo:14,500 mg/kg/15Y-I:EYE	CMAJAX Canadian Medical Association Journal. 132 (1985),737.
5.	orl-hmn LDLo:43 mg/kg	ARGPAQ Archives of General Psychiatry. 34 (1977),955.
6.	orl-chd TDLo:25 mg/kg:CNS,CVS	AJDCAI American Journal of Diseases of Children. 130 (1976),507.
7.	orl-hmn TDLo:24 mg/kg:ANS AACRAT 52,938,73
8.	orl-rat LD50:995 mg/kg	TXAPA9 Toxicology and Applied Pharmacology. 18 (1971),185.
9.	ipr-rat LD50:150 mg/kg	PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. 10 (1976),1001.
10.	scu-rat LD50:640 mg/kg	MDCHAG Medicinal Chemistry: A Series of Monographs. 4 (1967),199.

Thioridazine Consensus Reports

EPA Genetic Toxicology Program.

Thioridazine Safety Profile

Human poison by ingestion. Experimental poison by ingestion, subcutaneous, and intraperitoneal routes. Human systemic effects by ingestion: heart rate change, muscle contraction or spasticity, parasympatholytic, toxic psychosis, visual field and retinal changes. Human reproductive effects. Experimental reproductive effects. Mutation data reported. An antipsychotic and sedative. When heated to decomposition it emits very toxic fumes of NO_x and SO_x.

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