Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

Tipifarnib

Related Products

Hot Products

Name

Tipifarnib

EINECS N/A
CAS No. 192185-72-1 Density 1.334 g/cm3
PSA 65.84000 LogP 6.19670
Solubility N/A Melting Point 211-213 °C (dec.)
Formula C27H22Cl2N4O Boiling Point 681.725 °C at 760 mmHg
Molecular Weight 489.404 Flash Point 366.094 °C
Transport Information N/A Appearance Off-white to pale beige solid
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 192185-72-1 (Tipifarnib) Hazard Symbols N/A
Synonyms

S1453_Selleck;Zarnestra;Tipifarnib (Zarnestra);Tipifarnib;

Article Data 8

Tipifarnib Specification

The Tipifarnib with the cas number 192185-72-1 is also called 2(1H)-Quinolinone,6-[(R)-amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl-. The IUPAC name is 6-[(R)-amino-(4-chlorophenyl)-(3-methylimidazol-4-yl)methyl]-4-(3-
chlorophenyl)-1-methylquinolin-2-one. Its molecular formula is C27H22Cl2N4O. It is farnesyltranstransferase inhibitor.

The properties of the chemical are: (1)ACD/LogP: 4.94; (2)# of Rule of 5 Violations: 0  ; (3)#H bond acceptors: 5; (4)#H bond donors: 2; (5)#Freely Rotating Bonds: 5; (6)Polar Surface Area: 41.37 Å2; (7)Index of Refraction: 1.671; (8)Molar Refractivity: 137.33 cm3; (9)Molar Volume: 366.8 cm3; (10)Polarizability: 54.44×10-24cm3; (11)Surface Tension: 51.2 dyne/cm ; (12)Enthalpy of Vaporization: 100.02 kJ/mol ; (13)Vapour Pressure: 1.94×10-18 mmHg at 25°C.

You can still convert the following datas into molecular structure:
(1)SMILES: Clc1cccc(c1)C=3c2cc(ccc2N(C(=O)C=3)C)[C@@](N)(c4cncn4C)c5ccc(Cl)cc5
(2)InChI: InChI=1/C27H22Cl2N4O/c1-32-16-31-15-25(32)27(30,18-6-9-20(28)10-7-18)19-8-11-24-23(13-19)22(14-26(34)33(24)2)17-4-3-5-21(29)12-17/h3-16H,30H2,1-2H3/t27-/m1/s1
(3)InChIKey: PLHJCIYEEKOWNM-HHHXNRCGBH

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 192185-72-1