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| Name |
Tocofersolan |
EINECS | N/A |
| CAS No. | 9002-96-4 | Density | 1.01g/cm3 |
| PSA | 100.52000 | LogP | 8.38890 |
| Solubility | N/A | Melting Point |
34-38oC |
| Formula | C33H54O5.(C2H4O)n | Boiling Point | 662.7oC at 760mmHg |
| Molecular Weight | 795.108 | Flash Point | 195.4oC |
| Transport Information | N/A | Appearance | Clear, colorless solid. |
| Safety | Risk Codes | N/A | |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
Poly(oxy-1,2-ethanediyl),a-[4-[[3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl]oxy]-1,4-dioxobutyl]-w-hydroxy-, [2R-[2R*(4R*,8R*)]]-;D 1T;D-a-Tocopherol polyethylene glycol1000 succinate;D-a-Tocopheryl polyethylene glycol succinate;Eastman Vitamin ETPGS;TPGS;VE-TPGS 1000;VitE-TPGS;Vitamin E-TPGS;d-a-Tocopheryl poly(ethylene glycol) 1000 succinate;d-a-Tocopheryl polyethylene glycolsuccinate;a-Tocopheryl polyethylene glycolsuccinate; |
Tocofersolan Specification
The Tocofersolan is polyethylene glycol derivative of α-tocopherol with the formula C33H54O5.(C2H4O)n. The systematic name of this chemical is Poly(oxy-1,2-ethanediyl), alpha-(4-((3,4-dihydro-2,5,7,8-tetramethyl-2- (4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl)oxy)-1,4-dioxobutyl)-omega-hydroxy-, (2R-(2R*(4R*,8R*)))-. With the CAS registry number 9002-96-4, it is also named as alpha-Tocopheryl polyethylene glycol succinate. The other registry numbers are 162849-98-1, 249747-47-5, 30999-06-5 and 75139-00-3. It is a synthetic water-soluble version of vitamin E.
Uses of Tocofersolan: It is used as a vitamin E supplement or to treat vitamin E deficiency in individuals who cannot absorb fats due to disease. It is also used in cosmetics and pharmaceuticals as an antioxidant.
The following are the toxicity data which has been tested.
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| rat | LD50 | oral | > 7gm/kg (7000mg/kg) | Journal of Agricultural and Food Chemistry. Vol. 25, Pg. 273, 1977. |
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