Tretinoin

Molecular Structure:

Molecular Formula: C₂₀H₂₈O₂
Molecular Weight: 300.4351
IUPAC Name: (2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid
CAS NO: 1302-79-4
Classification Code of Tretinoin (CAS NO.302-79-4): Antineoplastic agents ; Dermatologic Agents ; Drug / Therapeutic Agent ; Keratolytic ; Keratolytic agents ; Mutation data ; Reproductive Effect ; Skin / Eye Irritant ; Tumor data
Melting point: 180-181 °C 
Index of Refraction: 1.556
Molar Refractivity: 95.52 cm³
Molar Volume: 297.1 cm³
Surface Tension: 39.1 dyne/cm
Density: 1.011 g/cm³
Flash Point: 350.6 °C
Enthalpy of Vaporization: 79.32 kJ/mol
Boiling Point: 462.8 °C at 760 mmHg
Vapour Pressure: 7.55E-10 mmHg at 25 °C 

 Tretinoin (CAS NO.302-79-4) has been used to treat acne and other skin problems, and can be used for the unusual type of acne, psoriasis ichthyosis and abnormal.

Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.

Poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. Experimental reproductive effects. Questionable carcinogen with experimental neoplastigenic and teratogenic data. Human mutation data reported. A human skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes.
Hazard Codes of  Tretinoin (CAS NO.302-79-4): T,Xn
Risk Statements: 22-63-38-20/21/22 
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed. 
R22:Harmful if swallowed. 
R38:Irritating to skin. 
R63:Possible risk of harm to the unborn child.
Safety Statements: 53-26-36/37/39-45-36/37 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S36/37:Wear suitable protective clothing and gloves. 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S53:Avoid exposure - obtain special instructions before use.

 Tretinoin , its cas register number is 302-79-4. It also can be called all-trans-Retinoic acid ; Vitamin A acid ; and 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid . It is the form of vitamin A that is referred to as retinoic acid or Retin-A. In this formulation, it can be applied directly to the skin to treat acne and other skin diseases, and also promotes cell differentiation and supports the growth and development of embryos in the body. It is hazardous, so the first aid measures and others should be known. Such as: When on the skin: first, should flush skin with plenty of water immediately for at least 15 minutes while removing contaminated clothing. Secondly, get medical aid. Or in the eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Then get medical aid soon. While, it's inhaled: Remove from exposure and move to fresh air immediately. Give artificial respiration while not breathing. When breathing is difficult, give oxygen. And as soon as to get medical aid. Then you have the ingesting of the product: Wash mouth out with water, and get medical aid immediately.
In addition, Tretinoin (CAS NO.302-79-4) could be stable under normal temperatures and pressures. It is not compatible with strong oxidizing agents, and you must not take it with incompatible materials. And also prevent it to broken down into hazardous decomposition products: carbon monoxide, carbon dioxide.