Tributylphosphine

Molecular Structure:

Molecular Formula: C₁₂H₂₇P
Molecular Weight: 202.316541 g/mol
Appearance: colorless pale yellow clear liquid
Melting Point: -65 °C
Boiling Point: 150 °C  at 50 mm Hg
Flash Point: 99 °F
Solubility: methanol, ether, ethanol, benzene
Insolubility: water
Density: 0.81 g/mL at 25 °C
Vapor density: 9
Refractive index:n: 20/D 1.462
Storage temp.: 2-8°C 
Sensitive: Moisture, Air
BRN: 1738261
EINECS: 213-651-2
IUPAC Name: tributylphosphane
Synonyms of Tributylphosphine (CAS NO.998-40-3): TRIBUTYLPHOSPHINE(998-40-3): Tri-n-butylphosphine ; 4-16-00-01699 (Beilstein Handbook Reference) ; AI3-28071 ; BRN 1738261 ; EINECS 213-651-2 ; NSC 91700 ; Tri-n-butylphosphine ; Tributylfosfin ; Tributylfosfin [Czech] ; Tributylphosphane ; Tributylphosphane [UN3254] [Spontaneously combustible] ; Tris(butyl)phosphine ; UN3254 ; Phosphine, tributyl-
Categories: Tertiary Phosphines;Ligand;Mitsunobu Reaction;Phosphine Ligands;Phosphines (Mitsunobu Reaction);Synthetic Organic Chemistry

 Tributylphosphine (CAS NO.998-40-3) is used as main ligand of homogeneous catalyst in the petrochemical. It is also used as reducing agent, olefin polymerization catalyst.

 Tributylphosphine (CAS NO.998-40-3) is prepared industrially by the reaction of phosphine with butene.
PH₃ + 3CH₂=CHCH₂CH₃ → P(CH₂CH₂CH₂CH₃)₃
It can be prepared in the laboratory by reaction of the appropriate Grignard reagent with phosphorus trichloride.
3BuMgCl + PCl₃ → PBu₃ + 3MgCl₂

Reported in EPA TSCA Inventory.

Safety Information of Tributylphosphine (CAS NO.998-40-3):
Hazard Codes:Xi  ,F  ,C
Risk Statements:36/38-34-21/22-17-11-37
36/38:Irritating to eyes and skin
11:Highly flammable
17:Spontaneously flammable in air
21/22:Harmful in contact with skin and if swallowed
34:Causes burns
Safety Statements:41-36/37/39-26-16-45-43-17-5
41:In case of fire and/or explosion do not breathe fumes
16:Keep away from sources of ignition - No smoking
26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36/37/39:Wear suitable protective clothing, gloves and eye/face protection
43:In case of fire, use ... (indicate in the space the precise type of fire-fighting equipment. If water increases the risk add - Never use water)
45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
17:Keep away from combustible material
5:Keep contents under ... (appropriate liquid to be specified by the manufacturer)
RIDADR:UN 3254 4.2/PG 1
WGK Germany:3
RTECS:SZ3270000
F:10-13-23
HazardClass:4.2
PackingGroup:I
Moderately toxic by ingestion. Slightly toxic by skin contact. When heated to decomposition it emits toxic vapors of PO_x.

First Aid Measures of Tributylphosphine (CAS NO.998-40-3):
Eyes:Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. 
Ingestion:Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Storage of Tributylphosphine (CAS NO.998-40-3):
Keep away from heat, sparks, and flame. Do not store near combustible materials. Store in a cool, dry place. Store in a tightly closed container. Flammables-area. Store under nitrogen.