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Triethylamine trihydrofluoride

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Name

Triethylamine trihydrofluoride

EINECS 277-550-5
CAS No. 73602-61-6 Density 0.989g/mLat 25°C(lit.)
PSA 3.24000 LogP 2.94620
Solubility completely soluble in water Melting Point -29 - -27 °C
Formula C6H15N.3HF Boiling Point 70°C15mm Hg(lit.)
Molecular Weight 161.211 Flash Point 90.5 °C at 760 mmHg
Transport Information UN 3265 8/PG 2 Appearance clear yellow liquid
Safety 26-36/37/39-45-7/9 Risk Codes 26/27/28-35
Molecular Structure Molecular Structure of 73602-61-6 (Triethylamine trihydrofluoride) Hazard Symbols VeryT+,CorrosiveC,IrritantXi
Synonyms

Ethanamine,N,N-diethyl-, trihydrofluoride (9CI);Triethylamine trihydrofluoride;Triethylamine tris(hydrogen fluoride);

Article Data 2

Triethylamine trihydrofluoride Synthetic route

76-37-9

2,2,3,3-tetrafluoropropanol

422-61-7

perfluoropropanoyl fluoride

A

73602-61-6

triethylamine tris(hydrogen fluoride)

B

1H,1H,3H-perfluoropropyl perfluoropropionate

Conditions
ConditionsYield
With triethylamine at 5 - 20℃; for 5h;A 88%
B 91%
2062-98-8, 125037-08-3

perfluoro(2-propoxypropionyl) fluoride

76-37-9

2,2,3,3-tetrafluoropropanol

A

73602-61-6

triethylamine tris(hydrogen fluoride)

B

1H,1H,3H-perfluoropropyl perfluoro-α-propoxypropionate

Conditions
ConditionsYield
With triethylamine at 5 - 20℃;
76-37-9

2,2,3,3-tetrafluoropropanol

375-84-8

2,2,3,3,4,4,5,5,6,6,7,7,7-tridecafluoroheptanoyl fluoride

A

73602-61-6

triethylamine tris(hydrogen fluoride)

B

1H,1H,3H-perfluoropropyl perfluoroenanthate

Conditions
ConditionsYield
With triethylamine at 5 - 20℃;
354-34-7

trifluoroacetyl fluoride

355-80-6

2,2,3,3,4,4,5,5-octafluoropentan-1-ol

A

79614-48-5

1,1,5-trihydroperfluoroamyl trifluoroacetate

B

73602-61-6

triethylamine tris(hydrogen fluoride)

Conditions
ConditionsYield
With triethylamine at 5 - 20℃;
38078-09-0

diethylamino-sulfur trifluoride

C6H15N*2FH*H(1+)*BF4(1-)

A

73602-61-6

triethylamine tris(hydrogen fluoride)

B

ethanaminium,N-(difluoro-λ4-sulfanylidene)-N-ethyl-,tetrafluoroborate

Conditions
ConditionsYield
In [D3]acetonitrile at 20℃; for 0.166667h; Inert atmosphere; Molecular sieve;
73602-61-6

triethylamine tris(hydrogen fluoride)

121-44-8

triethylamine

triethylammonium dihydrofluoride

Conditions
ConditionsYield
100%
In tetrahydrofuran
743460-39-1

biphenyl-2-ylcarbamic Acid 1-(2-{5-[(R)-2-(8-Benzyloxy-2-oxo-1,2-dihydroquinolin-5-yl)-2-(tert-butyldimethylsilanyloxy)ethylamino]pentylcarbamoyl}ethyl)piperidin-4-yl Ester

73602-61-6

triethylamine tris(hydrogen fluoride)

743460-40-4

biphenyl-2-ylcarbamic Acid 1-(2-{5-[(R)-2-(8-Benzyloxy-2-oxo-1,2-dihydroquinolin-5-yl)-2-hydroxyethylamino]pentylcarbamoyl}ethyl)piperidin-4-yl Ester

Conditions
ConditionsYield
In dichloromethane for 10h;100%

pyridin-1-ium [3-[4-[[tert-butyl(dimethyl)silyl]oxymethyl]pyrazol-1-yl]-7-oxo-1,6-diazabicyclo[3.2.1]oct-3-en-6-yl]sulfatee

73602-61-6

triethylamine tris(hydrogen fluoride)

triethylammonium [3-[4-(hydroxymethyl)pyrazol-1-yl]-7-oxo-1,6-diazabicyclo[3.2.1]oct-3-en-6-yl]sulfate

Conditions
ConditionsYield
In acetonitrile at 40℃; for 2.5h; Inert atmosphere;100%
743461-30-5

biphenyl-2-ylcarbamic Acid 1-{2-[3-(3-{[(R)-2-(tert-butyldimethylsilanyloxy)-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino]methyl}benzyl)ureido]ethyl}-piperidin-4-yl Ester

73602-61-6

triethylamine tris(hydrogen fluoride)

biphenyl-2-ylcarbamic acid 1-{2-[3-(3-{[(R)-2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino]methyl}benzyl)ureido]ethyl}piperidin-4-yl ester ditrifluoroacetate

Conditions
ConditionsYield
In dichloromethane at 20℃; for 15h;99%

[Au(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)(OtAm)]

73602-61-6

triethylamine tris(hydrogen fluoride)

C27H36AuFN2

Conditions
ConditionsYield
In benzene99%

Triethylamine trihydrofluoride Specification

The Triethylamine trihydrofluoride, with the CAS registry number 73602-61-6, is also known as Triethylamine tris(hydrogen fluoride). It belongs to the product categories of Fluorinating Reagents; Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds; Fluorination; Halogenation; Nucleophilic Fluorinating Reagents; Synthetic Organic Chemistry. Its EINECS number is 277-550-5. This chemical's molecular formula is C6H15N.3HF and molecular weight is 161.21. What's more, its systematic name is N,N-Diethylethanamine trihydrofluoride. Its classification code is TSCA Flag P [A commenced PMN (Premanufacture Notice) substance]. This chemical should be sealed and stored in a cool and dry place. Moreover, it should be protected from strong oxides, water and moisture.

Physical properties of Triethylamine trihydrofluoride are: (1)ACD/LogP: 1.657; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -1.44; (4)ACD/LogD (pH 7.4): -1.20; (5)ACD/BCF (pH 5.5): 1.00; (6)ACD/BCF (pH 7.4): 1.00; (7)ACD/KOC (pH 5.5): 1.00; (8)ACD/KOC (pH 7.4): 1.00; (9)#H bond acceptors: 1; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 3; (12)Polar Surface Area: 3.24 Å2; (13)Enthalpy of Vaporization: 31.01 kJ/mol; (14)Boiling Point: 90.5 °C at 760 mmHg; (15)Vapour Pressure: 56.1 mmHg at 25°C.

When you are using this chemical, please be cautious about it as the following:
This chemical is toxic if swallowed, and it is very toxic by inhalation, in contact with skin and if swallowed. It is irritating to eyes, respiratory system and skin. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. When using it, you need wear suitable protective clothing, gloves and eye/face protection. You should keep the container tightly closed and in a well-ventilated place. In case of accident or if you feel unwell, you must seek medical advice immediately (show the label where possible).

You can still convert the following datas into molecular structure:
(1)SMILES: F.F.F.N(CC)(CC)CC
(2)Std. InChI: InChI=1S/C6H15N.3FH/c1-4-7(5-2)6-3;;;/h4-6H2,1-3H3;3*1H
(3)Std. InChIKey: IKGLACJFEHSFNN-UHFFFAOYSA-N 

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