Basic information
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Chemistry
IUPAC Name: 1,4-Diazabicyclo[2.2.2]octane
The MF of 1,4-Diazabicyclo[2.2.2]octane (88935-43-7) is C6H12N2.
The MW of 1,4-Diazabicyclo[2.2.2]octane (88935-43-7) is 112.1729.
Synonyms of 1,4-Diazabicyclo[2.2.2]octane (88935-43-7): 1,4-Diazabicyclo[2.2.2]octan ; Triethylenediamine ; 1,4-Diazabicyclo-octane ; 1,4-Ethylenepiperazine
Appearance: white crystalline powder
Index of Refraction: 1.56
Density: 1.08 g/ml
Flash Point: 62.2 °C
Boiling Point: 374 °C
Melting Point: 155-160 °C
Solubility: Soluble in water
Uses
1,4-Diazabicyclo[2.2.2]octane (88935-43-7) is used as organic synthesis, pharmaceutical intermediates.
Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| guinea pig | LD50 | oral | 2250mg/kg (2250mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(5), Pg. 67, 1980. |
| rabbit | LD50 | oral | 1100mg/kg (1100mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(5), Pg. 67, 1980. |
| rat | LD50 | oral | 1700mg/kg (1700mg/kg) | Zeitschrift fuer die Gesamte Hygiene und Ihre Grenzgebiete. Vol. 20, Pg. 393, 1974. |