Triprolidine hydrochloride monohydrate (6138-79-0),Triprolidine hydrochloride monohydrate (6138-79-0) Manufacturers & Suppliers,Synthesis,MSDS

Basic information

Name:
Triprolidine hydrochloride monohydrate
Superlist Name:
Triprolidine hydrochloride
CAS No.:
6138-79-0
Molecular Structure:
Formula:
C₁₉H₂₂N₂^.HCl
Molecular Weight:
314.85
Synonyms:
Pyridine,2-[(1E)-1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]-, monohydrochloride,monohydrate (9CI);Pyridine,2-[1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]-, monohydrochloride,monohydrate, (E)-;Pyridine, 2-[3-(1-pyrrolidinyl)-1-p-tolylpropenyl]-,monohydrochloride, monohydrate, stereoisomer (8CI);Triprolidine hydrochloride;Pyridine,2-[(1E)-1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propen-1-yl]-, hydrochloride,hydrate (1:1:1);
Melting Point:
115-120 °C
Boiling Point:
462 °C at 760 mmHg
Flash Point:
233.2 °C
Solubility:
>=10 g/100 mL at 20 °C in water
Appearance:
White crystalline powder
Hazard Symbols:
Xn
Risk Codes:
22-36/37/38
Safety Description:
26-36 Details

Famous Chemical Enterprises

Livzon
Total
Shell
Dupont
Exxonmobil
Akzonobel
Basf
Bayer
BP

Other Products

Please post your buying leads,so that our qualified suppliers will soon contact you!
*Required Fields

Chemistry

IUPAC Name: 2-[(E)-1-(4-Methylphenyl)-3-pyrrolidin-1-ium-1-ylprop-1-enyl]pyridine chloride
Molecular Formula: C₁₉H₂₂N₂^.HCl
Molecular Weight: 314.85 g/mol
Canonical SMILES: C(\c1ccc(C)cc1)(c1ccccn1)=C/C[NH+]1CCCC1.[ClH-]
InChI: InChI=1/C19H22N2.ClH/c1-16-7-9-17(10-8-16)18(19-6-2-3-12-20-19)11-15-21-13-4-5-14-21;/h2-3,6-12H,4-5,13-15H2,1H3;1H/b18-11+;
Classification Code: Antihistaminic; Drug / Therapeutic Agent
Product Categories: Bulk Pharmaceuticals
Stability: Stable, but discolours in light. Incompatible with strong oxidizing agents.
Melting Point: 115-120 °C
Storage temperature: 2-8 °C
Water Solubility: >=10 g/100 mL at 20 °C
Flash Point: 233.2 °C
Enthalpy of Vaporization: 73.68 kJ/mol
Boiling Point: 462 °C at 760 mmHg
Vapour Pressure of Triprolidine hydrochloride monohydrate (CAS NO.6138-79-0): 6.16E-09 mmHg at 25 °C

Uses

Triprolidine hydrochloride monohydrate (CAS NO.6138-79-0) is used as bulk pharmaceutical (antihistaminic).

Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	oral	163mg/kg (163mg/kg)		National Center for Toxicology Research Technical Report. Office of Associate Director for Scientific Coordination, Jefferson, Arkansas 72079Vol. #414/415, Pg. 1991,
rat	LD50	oral	840mg/kg (840mg/kg)		National Center for Toxicology Research Technical Report. Office of Associate Director for Scientific Coordination, Jefferson, Arkansas 72079Vol. #414/415, Pg. 1991,

Safety Profile

Hazard Codes: Harmful Xn
Risk Statements: 22-36/37/38
R22: Harmful if swallowed.
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36: Wear suitable protective clothing.
WGK Germany: 3
RTECS of Triprolidine hydrochloride monohydrate (CAS NO.6138-79-0): UT7658000

Specification

Triprolidine hydrochloride monohydrate (CAS NO.6138-79-0), its Synonyms are (E)-2-(3-(1-Pyrrolidinyl)-1-p-tolylpropenyl)pyridine monohydrochloride monohydrate ; Actidil ; Myidyl ; Pyridine, 2-(1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl)-, monohydrochloride, monohydrate, (E)- ; Triprolidine HCl ; Triprolidine hydrochloride ; Pyridine, 2-(3-(1-pyrrolidinyl)-1-p-tolylpropenyl)-, monohydrochloride, monohydrate, stereoisomer . It is odorless white crystalline powder and bitter taste.