Basic information
- Name:
Ursolic acid
- CAS No.:
77-52-1
- Molecular Structure:
- Formula:
- C30H48O3
- Molecular Weight:
- 456.71
- Deleted CAS:
- 209545-05-1
- Synonyms:
- Ursolic Acid;Ursolicacid;Ursoliic acid;3beta-Hydroxyurs-12-en-28-oic acid;Prunol;Urs-12-en-28-oic acid, 3.beta.-hydroxy-;(3beta)-3-Hydroxyurs-12-en-28-oic acid;(1S,2R,4aS,6aS,6bR,10S,12aS,14bR)-10-hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid;Urson;10-hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid;Prestwick_355;(1S,2R,4aS,6aS,6aS,6bR,8aS,10S,12aS,14bR)-10-hydroxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid;Urs-12-en-28-oic acid, 3-hydroxy-, (3beta)-;Bungeolic acid;Urs-12-en-28-oic acid, 3-hydroxy-, (3.beta.)-;Urs-12-en-28-oic acid, 3beta-hydroxy- (8CI);
- EINECS:
- 201-034-0
- Density:
- 1.09 g/cm3
- Melting Point:
- 292 °C (dec.)(lit.)
- Boiling Point:
- 556.9 °C at 760 mmHg
- Flash Point:
- 304.7 °C
- Solubility:
- insoluble in water
- Appearance:
- white to light yellow crystal powder
- Hazard Symbols:
Xi- Risk Codes:
- 36/37/38
- Safety Description:
- 24/25-36-26 Details
- particular:
- particular
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Chemistry
Ursolic acid is a pentacyclic triterpene acid,Ursolic acid's other name is known as Prunol, Malol, Urson, beta-Ursolic acid,
Molecular formula :C30H48O3
Molar mass 456.70 g/mol
Uses
Ursolic acid can be used in cosmetics, and capable of inhibiting various types of cancer cells by inhibiting the STAT3 activation pathway and human fibrosarcoma cells by reducing the expression of matrix metalloproteinase-9 by acting through the glucocorticoid receptor.As medicine it is well tolerated and can be used topically and orally.
Production
Ursolic acid is present in many plants, including apples, bilberries, cranberries, elder flower, rosemary, lavender, oregano, thyme, prunes. Apple peels contain high quantity of ursolic acid and related compounds which are responsible for the anti-cancer activity of apple. Ursolic acid can also serve as a starting material for synthesis of more potent bioactive derivatives, such as anti-tumor agents.