Ethene, chloro-

In 1835, Vinyl chloride (CAS NO.75-01-4) was first produced by Justus von Liebig and his student Henri Victor Regnault. They obtained it by treating ethylene dichloride with a solution of potassium hydroxide in ethanol.
In 1912, Frans, a German chemist working for Griesheim-Elektron, patented a means to produce vinyl chloride from acetylene and hydrogen chloride using mercuric chloride as a catalyst. Whereas this method was widely used during the 1930s and 1940s, it has since been superseded by more economical processes, at least in the West.

NTP 10th Report on Carcinogens. IARC Cancer Review: Group 1 IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 373.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 19 ,1979,p. 377.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1974,p. 291.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Limited Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1974,p. 291.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Sufficient Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 19 ,1979,p. 377.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Community Right-To-Know List. Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.

OSHA PEL: Cancer Suspect Agent
ACGIH TLV: TWA 1 ppm; Confirmed Human Carcinogen
DFG MAK: DFG TRK: Confirmed Human Carcinogen
NIOSH REL: (Vinyl Chloride) Lowest Detectable Level
DOT Classification:  2.1; Label: Flammable Gas

For occupational chemical analysis use OSHA: #04 or NIOSH: Vinyl Chloride, 1007.

The Vinyl chloride, with the CAS registry number 75-01-4 and EINECS registry number 200-831-0, has the systematic name of chloroethene. And the molecular formula of this chemical is C₂H₃Cl. It is a kind of colourless gas with a sickly sweet odor, and also called VCM which is shourt for vinyl chloride monomer.

The physical properties of Vinyl chloride are as following: (1)ACD/LogP: 1.44; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 1.44; (4)ACD/LogD (pH 7.4): 1.44; (5)ACD/BCF (pH 5.5): 7.32; (6)ACD/BCF (pH 7.4): 7.32; (7)ACD/KOC (pH 5.5): 144.75; (8)ACD/KOC (pH 7.4): 144.75; (9)#H bond acceptors: 0; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 0; (12)Polar Surface Area: 0 Å²; (13)Index of Refraction: 1.383; (14)Molar Refractivity: 15.88 cm³; (15)Molar Volume: 68 cm³; (16)Polarizability: 6.29×10^-24cm³; (17)Surface Tension: 17.5 dyne/cm; (18)Density: 0.918 g/cm³; (19)Enthalpy of Vaporization: 23.04 kJ/mol; (20)Vapour Pressure: 2580 mmHg at 25°C.

Preparation of Vinyl chloride: It mainly prepared by two methods, the hydrochlorination of acetylene and the dehydrochlorination of ethylene dichloride (1,2-dichloroethane). And the production of vinyl chloride from 1,2-dichloroethane (EDC) consists of a series of well-defined steps. EDC is prepared by reacting ethylene and chlorine. In the presence of iron(III) chloride as a catalyst, these compounds react exothermically: CH₂=CH₂ + Cl₂→ ClCH₂CH₂Cl

Uses of Vinyl chloride: It is a chemical intermediate, and often used to produce polyvinyl chloride. And it is used as an inhalational anaesthetic, in a similar vein to ethyl chloride, though its toxicity forced this practice to be abandoned. In addition, it is also used as an aerosol propellant and is the starting material for polyvinyl resins.

You should be cautious while dealing with this chemical. It is a kind of extremely flammable chemical, and has danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed. What's more, it may also cause cancer. Therefore, you had better take the following instructions: Wear suitable protective clothing and gloves; Avoid exposure - obtain special instruction before use; In case of accident or if you feel unwell, seek medical advice immediately (show label where possible).

You can still convert the following datas into molecular structure:
(1)SMILES: Cl\C=C
(2)InChI: InChI=1/C2H3Cl/c1-2-3/h2H,1H2
(3)InChIKey: BZHJMEDXRYGGRV-UHFFFAOYAW

The toxicity data is as follows: