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Chemistry informtion about N-Methyl-O,O-Dimethylthiolophos-Phoryl-5-Thia-3-Methyl-2-Valeramide (CAS NO.2275-23-2) is:
IUPAC Name: 2-(2-Dimethoxyphosphorylsulfanylethylsulfanyl)-N-Methylpropanamide
Synonyms: Vamidothion ; Vamidothion(Content>10%) ; 10465rp ; 2-(2-Dimethoxyphosphinoylthioethylthio)-N-Methylpropionamide ; Americancyanamid-43073 ; Dimethyls-(2-(1-Methylcarbamoylethylthio)Ethyl)Phosphorothiolate ; Ent26,613 ; N-Methyl-3-Thia-2-Methyl-Valeramiddero,O-Dimethylthiolphosphorsaeure
MF: C8H18NO4PS2
MW: 287.34
EINECS: 218-894-8
Density: 1.24 g/cm3
Flash Point: 2 °C
Storage temp.: 0-6°C
Following is the molecular structure of N-Methyl-O,O-Dimethylthiolophos-Phoryl-5-Thia-3-Methyl-2-Valeramide (CAS NO.2275-23-2) is:
N-Methyl-O,O-Dimethylthiolophos-Phoryl-5-Thia-3-Methyl-2-Valeramide (CAS NO.2275-23-2) is a systemic acaricide and insecticide.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
bird - wild | LD50 | oral | 35mg/kg (35mg/kg) | Pesticide Manual. Vol. 9, Pg. 856, 1991. | |
cat | LD50 | unreported | 117mg/kg (117mg/kg) | behavioral: ataxia behavioral: coma kidney, ureter, and bladder: urine volume increased | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 41(3), Pg. 107, 1976. |
dog | LD50 | oral | 110mg/kg (110mg/kg) | Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 530, 1973. | |
guinea pig | LD50 | oral | 85mg/kg (85mg/kg) | Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 530, 1973. | |
guinea pig | LD50 | unreported | 85mg/kg (85mg/kg) | "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 349, 1971. | |
mouse | LD50 | oral | 40mg/kg (40mg/kg) | behavioral: tremor | Meditsinskii Zhurnal Uzbekistana. Vol. (8), Pg. 65, 1972. |
mouse | LD50 | skin | 1460mg/kg (1460mg/kg) | Yakkyoku. Pharmacy. Vol. 37, Pg. 1621, 1986. | |
mouse | LD50 | unreported | 43mg/kg (43mg/kg) | "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 349, 1971. | |
rabbit | LD50 | oral | 160mg/kg (160mg/kg) | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 14(2), Pg. 58, 1970. | |
rabbit | LD50 | skin | 1160mg/kg (1160mg/kg) | World Review of Pest Control. Vol. 9, Pg. 119, 1970. | |
rat | LC50 | inhalation | 1730mg/m3/4H (1730mg/m3) | Pesticide Manual. Vol. 9, Pg. 856, 1991. | |
rat | LD50 | oral | 64mg/kg (64mg/kg) | "Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969Vol. 5, Pg. 233, 1976. | |
rat | LD50 | unreported | 64mg/kg (64mg/kg) | "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971Vol. -, Pg. 349, 1971. |
EPA Genetic Toxicology Program.
Poison by ingestion and skin contact. Mutation data reported. When heated to decomposition it emits very toxic fumes of POx, SOx, and NOx.
Hazard Codes:
T
N
Xn
F
Risk Statements:
R21:Harmful in contact with skin.
R25 :Toxic if swallowed.
R50:Very toxic to aquatic organisms.
R36:Irritating to eyes.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
R11:Highly flammable.
Safety Statements:
S36/37:Wear suitable protective clothing and gloves.
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
S16:Keep away from sources of ignition.
RIDADR: UN 2811
RTECS: TF7900000
HazardClass: 6.1(b)
PackingGroup: III
N-Methyl-O,O-Dimethylthiolophos-Phoryl-5-Thia-3-Methyl-2-Valeramide (CAS NO.2275-23-2) is a colorless needles.
First Aid Measures:
Ingestion: Seek medical assistance.
Inhalation: Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
Skin: Systemic effects can occur from dermal exposure to organophosphates. Remove contaminated clothing, wash skin, hair and nails vigorously with repeated soap washings. Leather absorbs pesticides; all contaminated leather should be discarded. Rescue personnel and bystanders should avoid direct contact with contaminated skin, clothing, or other objects. Treatment should include recommendations listed in the oral exposure section when appropriate.
Eyes: Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility. Patients symptomatic following exposure should be observed in a controlled setting until all signs and symptoms have fully resolved. Treatment should include recommendations listed in the oral exposure section when appropriate.
Handling and Storage:
Storage: Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling: All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.