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Cas Database |
| Name |
Veratramine |
EINECS | N/A |
| CAS No. | 60-70-8 | Density | 1.14g/cm3 |
| PSA | 52.49000 | LogP | 4.92330 |
| Solubility | N/A | Melting Point |
122-1240C |
| Formula | C27H39 N O2 | Boiling Point | 565°C at 760 mmHg |
| Molecular Weight | 409.612 | Flash Point | 86.2°C |
| Transport Information | N/A | Appearance | N/A |
| Safety | Poison by ingestion, intravenous, and subcutaneous routes. An experimental teratogen. When heated to decomposition it emits toxic fumes of NOx. | Risk Codes | N/A |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
Veratraman-3,23-diol,14,15,16,17-tetradehydro-, (3b,23b)-; Veratramine (7CI,8CI);1H-Benzo[a]fluorene, veratraman-3,23-diol deriv.; NSC 17821; NSC 23880 |
Article Data | 5 |
Veratramine Chemical Properties
IUPAC Name: (2S,3R,5S)-2-[(1S)-1-[(3S,6aR,11aS,11bR)-3-hydroxy-10,11b-dimethyl-1,2,3,4,6,6a,11,11a-octahydrobenzo[a]fluoren-9-yl]ethyl]-5-methylpiperidin-3-ol
Synonyms: Veratramine ; Vreaframine ; (3b,23b)-14,15,16,17-Teradehydroveratraman-3,23-diol ; (3,23)-14,15,16,17-Teradehydroveratraman-3,23-diol
Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals
Molecular Formula of Veratramine (CAS NO.60-70-8) : C27H39NO2
Molecular Weight: 409.6041 g/mol
Structure of Veratramine (CAS NO.60-70-8) :
.bmp)
Index of Refraction: 1.601
Surface Tension: 50.5 dyne/cm
Density: 1.14 g/cm3
Flash Point: 86.2 °C
Enthalpy of Vaporization: 89.29 kJ/mol
Boiling Point: 565 °C at 760 mmHg
Vapour Pressure: 1.33E-13 mmHg at 25°C
Melting point: 122-1240°C
Appearance: White Solid
Veratramine Uses
Veratramine (CAS NO.60-70-8) is useful as signal transduction inhibitor for treating tumors.
Veratramine Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intravenous | 3100ug/kg (3.1mg/kg) | Cesko-Slovenska Farmacie. Vol. 2, Pg. 418, 1953. | |
| mouse | LD50 | subcutaneous | 4500ug/kg (4.5mg/kg) | BEHAVIORAL: TREMOR BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Journal of Pharmacology and Experimental Therapeutics. Vol. 113, Pg. 89, 1955. |
| rabbit | LDLo | oral | 33mg/kg (33mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: TREMOR | Teratology, The International Journal of Abnormal Development. Vol. 3, Pg. 175, 1970. |
Veratramine Safety Profile
Poison by ingestion, intravenous, and subcutaneous routes. An experimental teratogen. When heated to decomposition Veratramine (CAS NO.60-70-8) emits toxic fumes of NOx.
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