- 14293-50-6Benzoic acid,5-(aminosulfonyl)-4-chloro-2-hydroxy-, methyl ester
- 142935-44-23,3-diethyl-4-oxoazetidin-2-yl propionate
- 142937-50-61,4,7(4bH)-Phenanthrenetrione,5,6,8,8a,9,10-hexahydro-8-(hydroxymethyl)-4b,8-dimethyl-2-(1-methylethyl)-,(4bS,8S,8aR)-
- 14294-09-81-Piperidinecarbothioamide
- 14294-11-2Thiourea,N-2-pyridinyl-
- 142944-38-51H-Pyrido[3,4-b]indol-1-one,2,3,4,9-tetrahydro-2-[3-(4-phenyl-1-piperazinyl)propyl]-
- 142948-07-0Adenosine,2'-deoxy-8-(phenylmethoxy)- (9CI)
- 142948-08-1Adenosine,N-benzoyl-2'-deoxy-7,8-dihydro-8-oxo- (9CI)
- 142-94-9Octadecanoic acid,2-bromo-
- 142-95-01-Octanamine,hydrochloride (1:1)
Hot Products
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
- 7631-86-9Silicon dioxide
- 302-79-4Tretinoin
- 77-92-9Citric acid
|
Basic Information |
|
Post buying leads |
|
Suppliers |
|
Cas Database |
| Name |
Xipamide |
EINECS | 238-216-4 |
| CAS No. | 14293-44-8 | Density | 1.477 g/cm3 |
| PSA | 117.87000 | LogP | 4.41620 |
| Solubility | 58mg/L(25 oC) | Melting Point |
255-256 °C |
| Formula | C15H15ClN2O4S | Boiling Point | N/A |
| Molecular Weight | 354.814 | Flash Point | N/A |
| Transport Information | N/A | Appearance | N/A |
| Safety | 26 | Risk Codes | 36/37/38 |
| Molecular Structure |
|
Hazard Symbols | Xi |
| Synonyms |
2',6'-Salicyloxylidide,4-chloro-5-sulfamoyl- (8CI);Aquaphor;Aquaphor (diuretic);BE 1293;BEI 1293;Chronexan;Diurex (Lacer);Diurexan;Lumitens;MJF 10938; |
Article Data | 2 |
Xipamide Chemical Properties
Product Name: Xipamide (CAS NO.14293-44-8)
MF: C15H15ClN2O4S
MW: 354.81
Index of Refraction: 1.652
Melting Point: 255-256 °C
EINECS: 238-216-4
Index of Refraction: 1.652
Molar Refractivity: 87.89 cm3
Molar Volume: 40.1 cm3
Surface Tension: 67.1 dyne/cm
Density: 1.477 g/cm3
XLogP3-AA: 2.9
H-Bond Donor: 3
H-Bond Acceptor: 5
Structure Descriptors of Xipamide (CAS NO.14293-44-8):
IUPAC Name: 4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-5-sulfamoylbenzamide
Canonical SMILES: CC1=C(C(=CC=C1)C)NC(=O)C2=CC(=C(C=C2O)Cl)S(=O)(=O)N
InChI: InChI=1S/C15H15ClN2O4S/c1-8-4-3-5-9(2)14(8)18-15(20)10-6-13(23(17,21)22)11(16)7-12(10)19/h3-7,19H,1-2H3,(H,18,20)(H2,17,21,22)
InChIKey: MTZBBNMLMNBNJL-UHFFFAOYSA-N
Product Categories: APIs; Xipamide
Xipamide Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| dog | LD50 | intravenous | > 50mg/kg (50mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 25, Pg. 245, 1975. | |
| dog | LD50 | oral | > 1500mg/kg (1500mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 25, Pg. 245, 1975. | |
| mouse | LD50 | intraperitoneal | 520mg/kg (520mg/kg) | BEHAVIORAL: ATAXIA BEHAVIORAL: COMA LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Arzneimittel-Forschung. Drug Research. Vol. 25, Pg. 245, 1975. |
| mouse | LD50 | oral | 877mg/kg (877mg/kg) | United States Patent Document. Vol. #4490368, | |
| mouse | LD50 | subcutaneous | 1480mg/kg (1480mg/kg) | BEHAVIORAL: ATAXIA BEHAVIORAL: COMA LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Arzneimittel-Forschung. Drug Research. Vol. 25, Pg. 245, 1975. |
| rat | LD50 | intraperitoneal | 320mg/kg (320mg/kg) | BEHAVIORAL: ATAXIA BEHAVIORAL: COMA LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Arzneimittel-Forschung. Drug Research. Vol. 25, Pg. 245, 1975. |
| rat | LD50 | oral | 1640mg/kg (1640mg/kg) | BEHAVIORAL: ATAXIA BEHAVIORAL: COMA LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION | Arzneimittel-Forschung. Drug Research. Vol. 25, Pg. 245, 1975. |
Xipamide Safety Profile
Poison by intraperitoneal route. Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits toxic fumes of Cl−, SOx, and NOx.
Xipamide Specification
Xipamide , its CAS NO. is 14293-44-8, the synonyms are 4-Chloro-2',6'-dimethyl-5-sulfamoylsalicylanilide ; 4-Chloro-5-sulfamylsalicyloyl-2',6'-dimethylanilide ; 4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy-5-sulfamoylbenzamide ; 5-(Aminosulfonyl)-4-chloro-N-(2,6-dimethylphenyl)-2-hydroxybenzamide ; Benzamide, 5-(aminosulfonyl)-4-chloro-N-(2,6-dimethylphenyl)-2-hydroxy- ; 2',6'-Salicyloxylidide, 4-chloro-5-sulfamoyl- .
What can I do for you?
Get Best Price
