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Name	Zeaxanthin	EINECS	205-636-4
CAS No.	144-68-3	Density	1.008 g/cm³
PSA	40.46000	LogP	10.54740
Solubility	insoluble in water	Melting Point	203-205 °C
Formula	C₄₀H₅₆O₂	Boiling Point	711.4 °C at 760 mmHg
Molecular Weight	568.883	Flash Point	273.4 °C
Transport Information	N/A	Appearance	yellow crystalline solid
Safety		Risk Codes	N/A
Molecular Structure		Hazard Symbols	N/A
Synonyms	all-trans-Anchovyxanthin;all-trans-Zeaxanthin;Zeaxanthin(7CI);b-Carotene-3,3'-diol, (3R,3'R)-all-trans- (6CI,8CI);(3R,3'R)-Zeaxanthin;Anchovyxanthin;Anchovyxanthin, all-trans-;Xanthophyll 3;ZeaGold;Zeaxanthin,all-trans-;Zeaxanthol;	Article Data	50

Zeaxanthin Synthetic route

: 7481-64-3
all-trans lutein

: 144-68-3
zeaxanthin

Conditions

Conditions	Yield
With ethanol; sodium ethanolate; benzene at 100 - 110℃;

: 14656-56-5, 26543-85-1
3,3'-di-keto-β-carotene

: 555-31-7
aluminum isopropoxide

: 67-63-0
isopropyl alcohol

: 71-43-2
benzene

: 144-68-3
zeaxanthin

: 15486-31-4
(2E,4E,6E,8E,10E,12E,14E)-15-(4-hydroxy-2,6,6-trimethylcyclohex-1-en-1-yl)-4,9,13-trimethylpentadeca-2,4,6,8,10,12,14-heptaenal

: <3-(4-hydroxy-2,2,6-trimethylcyclohexenyl)-1-methyl-2-propen-1-yl>triphenylphosphonium bromide

: 144-68-3
zeaxanthin

Conditions

Conditions	Yield
With potassium hydroxide In isopropyl alcohol at 20℃; for 3h;	8.5 mg

: zeaxanthin radical cation

: 144-68-3
zeaxanthin

Conditions

Conditions	Yield
With TX-100 In water Rate constant; Irradiation;

: 116-30-3
4',5'-didehydro-4,5'-retro-β,β-carotene-3,3'-dione

A: 144-68-3
zeaxanthin

B: 127-40-2
lutein

C: 89673-72-3
(3R,3'S,6'R)-lutein

Conditions

Conditions	Yield
With tellurium; sodium tetrahydroborate In carbon disulfide; ethanol at 40℃; for 0.333333h; Title compound not separated from byproducts;	A 24 % Chromat. B 44 % Chromat. C 31 % Chromat.
With tellurium; sodium tetrahydroborate In carbon disulfide; ethanol at 40℃; for 0.333333h;	A 24 % Chromat. B 44 % Chromat. C 31 % Chromat.

: 502-65-8
lycopene

: zeaxanthin radical cation

A: 144-68-3
zeaxanthin

B: lycopene radical cation

Conditions

Conditions	Yield
In benzene Rate constant; pulse radiolysis;

all-trans-β-carotenedione-(3,3'): all-trans-β-carotenedione-(3,3')

: 144-68-3
zeaxanthin

Conditions

Conditions	Yield
With aluminum isopropoxide; isopropyl alcohol; benzene

: 53163-53-4
(E)-4,9-dimethyl-2,4,6,8,10-dodecapentaene-1,12-dial

4-triphenylphosphoranylidene-pent-2t(?)-enoic acid methyl ester: 4-triphenylphosphoranylidene-pent-2t(?)-enoic acid methyl ester

: 144-68-3
zeaxanthin

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 11 mg / aq. KOH / propan-2-ol / 24 h / 20 °C 2: 8.5 mg / aq. KOH / propan-2-ol / 3 h / 20 °C View Scheme

: 32469-38-8
4-(1,4-dihydroxy-2,2,6-trimethylcyclohexyl)-3-butyn-2-ol

: 144-68-3
zeaxanthin

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: 3.5 g / lithium aluminium hydride / tetrahydrofuran / 3 h / Heating 2: 2.21 g / CHCl3 / 18 h / 20 °C 3: 11 mg / aq. KOH / propan-2-ol / 24 h / 20 °C 4: 8.5 mg / aq. KOH / propan-2-ol / 3 h / 20 °C View Scheme
Multi-step reaction with 3 steps 1: 3.5 g / lithium aluminium hydride / tetrahydrofuran / 3 h / Heating 2: 2.21 g / CHCl3 / 18 h / 20 °C 3: 8.5 mg / aq. KOH / propan-2-ol / 3 h / 20 °C View Scheme

: 53342-69-1
4-(4-hydroxy-2,2,6-trimethylcyclohexylidene)-3-buten-2-ol

: 144-68-3
zeaxanthin

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: 2.21 g / CHCl3 / 18 h / 20 °C 2: 11 mg / aq. KOH / propan-2-ol / 24 h / 20 °C 3: 8.5 mg / aq. KOH / propan-2-ol / 3 h / 20 °C View Scheme
Multi-step reaction with 2 steps 1: 2.21 g / CHCl3 / 18 h / 20 °C 2: 8.5 mg / aq. KOH / propan-2-ol / 3 h / 20 °C View Scheme

Zeaxanthin Chemical Properties

IUPAC Name: (1R)-4-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4R)-4-hydroxy-2,6,6-trimethylcyclohexen-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-3,5,5-trimethylcyclohex-3-en-1-ol
Synonyms of Zeaxanthin (CAS NO.144-68-3): 3R 3'R Zeaxanthin ; (3R,3'R)-beta,beta-Carotene-3,3'-diol
CAS NO: 144-68-3
Molecular Formula: C₄₀H₅₆O₂
Molecular Weight: 568.88
Molecular Structure:
EINECS: 205-636-4
H bond acceptors: 2
H bond donors: 2
Freely Rotating Bonds: 12
Polar Surface Area: 18.46 Å²
Index of Refraction: 1.585
Molar Refractivity: 189.11 cm³
Molar Volume: 564.1 cm³
Surface Tension: 41.2 dyne/cm
Density: 1.008 g/cm³
Flash Point: 273.4 °C
Enthalpy of Vaporization: 118.87 kJ/mol
Boiling Point: 711.4 °C at 760 mmHg
Vapour Pressure: 2.19E-23 mmHg at 25°C
Melting Point: 203-205°C
Storage temp: -20°C
Appearance: Yellow Crystalline Solid
Product Categories of Zeaxanthin (CAS NO.144-68-3): Carotenoids;Intermediates & Fine Chemicals;Pharmaceuticals

Zeaxanthin Uses

Zeaxanthin (CAS NO.144-68-3) is used as a food additive, zeaxanthin is a food dye with E number E161h.

Zeaxanthin Safety Profile

F: 3-8-10

Zeaxanthin Specification

Natural occurrence of Zeaxanthin (CAS NO.144-68-3):
Zeaxanthin is one of the most common carotenoid alcohols found in nature. It is the pigment that gives paprika (made from bell peppers), corn, saffron, and many other plants their characteristic color and Zeaxanthin breaks down to form picrocrocin and safranal, which are responsible for the taste and aroma of saffron.

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