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| Name |
Zorubicin |
EINECS | 253-076-4 |
| CAS No. | 54083-22-6 | Density | 1.54g/cm3 |
| PSA | 210.23000 | LogP | 3.33700 |
| Solubility | N/A | Melting Point |
N/A |
| Formula | C34H35 N3 O10 | Boiling Point | °Cat760mmHg |
| Molecular Weight | 645.6558 | Flash Point | °C |
| Transport Information | N/A | Appearance | White or almost white crystalline powder |
| Safety | Risk Codes | N/A | |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
Benzoicacid, [1-[(2S,4S)-4-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl]ethylidene]hydrazide(9CI); Benzoic acid, [1-[4-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl]ethylidene]hydrazide,(2S-cis)-; Daunomycin benzoylhydrazone; MCMC 4222; Rubidazon; Rubidazone;Zorubicin |
Zorubicin Chemical Properties
IUPAC Name: N-[(E)-1-[(2S,4S)-4-(4-Amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]ethylideneamino]benzamide
Synonyms: (2S-cis)-Benzoic Acid [1-[4-[(3-Amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-napthacenyl]ethylidene]hydrazide ; Benzoic Acid Hydrazide 3-Hydrazone with Daunorubicin ; Benzoic acid, [(1E)-1-[(2S,4S)-4-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl]ethylidene]hydrazide ; Benzoic acid, 2-[(1E)-1-[(2S,4S)-4-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenyl]ethylidene]hydrazide
CAS NO: 54083-22-6
Molecular Formula of Rubidazone (CAS NO.54083-22-6) : C34H35N3O10
Molecular Weight of Rubidazone (CAS NO.54083-22-6) : 645.66
Molecular Structure of Rubidazone (CAS NO.54083-22-6) : 
Index of Refraction: 1.705
Surface Tension: 62.9 dyne/cm
Density: 1.54 g/cm3
Zorubicin Uses
Rubidazone (benzoylhydrazone daunorubicin) is a semisynthetic compound with a good experimental antitumor activity. Its main interest is its lower toxicity and cardiotoxicity. In human chemotherapy, it is considered a valuable drug.
Zorubicin Toxicity Data With Reference
| 1. | mmo-sat 10 µg/plate | EJCODS European Journal of Cancer and Clinical Oncology. 19 (1983),641. | ||
| 2. | dni-hmn:oth 500 µg/L | CCPHDZ Cancer Chemotherapy and Pharmacology. 2 (1979),31. |
Zorubicin Safety Profile
Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also RUBIDAZONE MONOHYDROCHLORIDE.
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