Reference

Antitumor activity of some amino acid metal systems

Antitumor activity of some amino acid metal systems. Banner, R. J.; Charlson, A. J.; Gale, R. P.; McArdle, N. T.; Trainor, K. E.; Watton, E. C. (Sch. Chem., Macquarie Univ., North Ryde, Aust.). Cancer Treat. Rep., 61(3), 469-70 (English) 1977. CODEN: CTRRDO. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) L-glutamine-K tetrochloroplatinate (II) complex, L-glutamine-K tetrachloropalladate(II) complex, L-serine-K tetrachloroplatinate (II) complex, and glycine-K tetrachloroplatinate (II) complex, showed antileukemic activity in mice, but K tetrachloroplatinate (II) [10025-99-7] and K tetrachloropalladate [10025-98-6] were ineffective. Apparently, the antitumor activity is produced by the complex species formed from the amino acids and the metal salts.

Magnetic circular dichroism and electronic states of tetrachloroplatinate(II) and tetrachloropalladate(II) ions

Magnetic circular dichroism and electronic states of tetrachloroplatinate(II) and tetrachloropalladate(II) ions. Nakayama, Kazuhiko; Komorita, Takashi; Shimura, Yoichi (Fac. Sci., Osaka Univ., Toyonaka 560, Japan). 10025-98-6 and 10025-99-7 are also occured in this study. Bull. Chem. Soc. Jpn., 57(4), 972-9 (English) 1984. CODEN: BCSJA8. ISSN: 0009-2673. DOCUMENT TYPE: Journal CA Section: 73 (Optical, Electron, and Mass Spectroscopy and Other Related Properties) The magnetic CD (MCD) spectra of K2PtCl4 and K2PdCl4 were carefully remeasured over the visible-near-UV region. The examn. of the electronic absorption and the MCD spectra together with their gaussian analyses strongly suggests that the band of K2PtCl4 at 30.3 ′ 103 cm-1 contains both G5(1Eg) and G3(1B1g) ?G1(1A1g) transitions, and the band of K2PdCl4 at 21.1 ′ 103 cm-1 all 3 spin-allowed l-l transitions. The sepn. of the G1(1A2g) and G5(1Eg) excited states is considerably greater for K2PtCl4 as compared with K2PdCl4. The MCD for the high-intensity absorption bands in K2PtCl4 is different from that reported previously. On the basis of new MCD result, the bands at 43.3 and 46.6 ′ 103 cm-1 were assigned to d-p transitions, a2u(pz) ?a1g(dz2) and eg(dxz,yz), resp. .