Reference

Toxicity studies of cobalt sulfate heptahydrate (CAS No

Toxicity studies of cobalt sulfate heptahydrate (CAS No. 10026-24-1) in F344/N rats and B6C3F1 mice (inhalation studies). Bucher, J. R. (Natl. Toxicol. Program, Research Triangle Park, NC, USA). Report, NTP-TOX-5, NIH/PUB-91-3124; Order No. PB91-185348, 44 pp. Avail. NTIS From: Gov. Rep.Some commonly used reagents like 10026-24-1 and 13825-86-0 are used in this experiment. Announce. Index (U. S.) 1991, 91(16), Abstr. No. 143,949 (English) 1991. DOCUMENT TYPE: Report CA Section: 4 (Toxicology) Toxicol. studies of cobalt sulfate heptahydrate (99% pure) were conducted by exposing groups of F344/N rats and B6C3F1 mice of each sex to a cobalt sulfate heptahydrate aerosol 6 h per day, 5 days per wk, for 15 days or 13 wk. In 16-day studies, all rats and mice exposed at the top concn. of 200 mg cobalt sulfate/m3 died (5 animals per group); partial survival was seen in the 50 mg/m3 exposure groups. Degeneration of the olfactory epithelium and necrotizing inflammation occurred in the nose of all rats and mice that died and in animals exposed to 50 mg/m3. Necrotizing inflammation was obsd. in the larynx and trachea of rats and mice at concns. as low as 5 mg/m3, and a similar lesion was present in the bronchi at exposure concns. of 50 mg/m3 or higher. Regenerative and inflammatory lesions, including peribronchial and septal fibrosis in the lung, were found in rats and mice exposed to 50 mg/m3 in 13-wk studies, all rats, all female mice, and all but 2 male mice exposed at the top concn. survived to the end of the studies (target exposure concns. of 0, 0.3, 1, 3, 10, and 30 mg/m3, 10 animals per group). The most sensitive tissue was the larynx, with squamous metaplasia obsd. in rats and mice at the lowest exposure concn. of 0.3 mg/m3. Thus, a no-obsd.-adverse-effect level was not reached in the studies. .

Solid-liquid separation after liquid-liquid extraction: spectrophotometric determnation of iron(II) by extraction of its ternary complex with 2,2'-dipyridyl and tetraphenylborate into molten naphthalene

Solid-liquid separation after liquid-liquid extraction: spectrophotometric determnation of iron(II) by extraction of its ternary complex with 2,2'-dipyridyl and tetraphenylborate into molten naphthalene. Satake, Masatada; Nagahiro, Toru; Puri, Bal Krishan (Fac. Eng., Fukui Univ., Fukui 910, Japan). Analyst (London), 109(1), 31-4 (English) 1984. CODEN: ANALAO. ISSN: 0003-2654. DOCUMENT TYPE: Journal CA Section: 79 (Inorganic Analytical Chemistry) A method for the spectrophotometric detn. of Fe(II) after extn. of its ternary complex with 2,2'-bipyridyl and Ph4B- into molten naphthalene was developed. Fe(II) reacts with 2,2'-bipyridyl to form a water-sol. colored complex. This complex cation forms a water-insol. stable ternary complex in the presence of NaBPh4, which is easily extd. into molten naphthalene at pH 2.8-7.6 by vigorous shaking for a few seconds. The solid naphthalene contg. the Fe 2,2'-bipyridyl tetraphenylborate complex is sepd. by filtration and dissolved in MeCN. The absorbance is measured at 521 nm against a reagent blank. Beer's law is obeyed in the concn. range 2.2-65. 10026-24-1 and 143-66-8 which are cas registry numbers of chemicals are mentioned.5 mg Fe/10 mL MeCN soln. The molar absorptivity and Sandell sensitivity are 8.89 ′ 103 L/mol cm and 0.0063 mg/cm2 at 521 nm, resp. The interference of various ions was studied in detail. The method was applied to the detn. of Fe in std. metallic samples and the results are compared with those obtained by the 1,10-phenanthroline method. .