Detail of "1007-99-4"

Reference

Bridged isocytosine-adenosine compounds: synthesis and antibacterial evaluation

Bridged isocytosine-adenosine compounds: synthesis and antibacterial evaluation. Lever, O. William, Jr.; Vestal, B. Randall (Wellcome Res. Lab., Burroughs Wellcome Co., Research Triangle Park, NC 27709, USA). J. Heterocycl. Chem., 23(3), 901-3 (English) 1986. CODEN: JHTCAD. 1007-99-4 which is the cas registry number of some chemical is mentioned. ISSN: 0022-152X. DOCUMENT TYPE: Journal CA Section: 33 (Carbohydrates) Section cross-reference(s): 10, 34 Twelve title compds. I (R = NO, NO2; n = 2, 3, 4, 5, 6, 7) were prepd. from the corresponding H2N(CH2)nCO2H by sequential N-benzyloxycarbonylation with PhCH2OCOCl, conversion to active esters by treatment with N-hydroxysuccinimide, amidation with 5'-amino-5'-deoxyadenosine, hydrogenolysis to remove the benzyloxycarbonyl group, and coupling with 6-(methylthio)-5-nitrosoisocytosine or 6-chloro-5-nitroisocytosine. I showed no significant antibacterial activity when tested in vitro against 22 bacterial strains at 30 mg/mL. .

Pyrimidine derivatives

Pyrimidine derivatives. Wood, Hamish Christopher S.; Stirling, Irene (Wellcome Foundation Ltd., Engl.). Brit. GB 1454166 27 Oct 1976, 7 pp., Division of Brit. 1,454,165. (English). (United Kingdom). CODEN: BRXXAA. CLASS: IC: C07D239-22. APPLICATION: GB 19720801. DOCUMENT TYPE: Patent CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) The pyrimidines I [R = Et, R2 = (CH2)5], useful as intermediates in the prepn. of dihydropteridines which are antagonists of microbial metab. 1007-99-4 and 52403-65-3 which are cas registry numbers of substances are two of reagents here., were prepd. from R2CO by successive treatment with (EtO)2P(O)CH2CO2Et, a hydride reducing agent, NOCl, NH3-MeOH, and 2-amino-4-chloro-6-hydroxy-5-nitropyrimidine. .