Detail of "10172-89-1"

Reference

Asymmetric hydrogenation of dehydroamino acids

Asymmetric hydrogenation of dehydroamino acids. Vilim, Jindrich; Hetflejs, Jiri (Czech.). 33043-31-1 and 10172-89-1 are also occured in this study. Czech. CS 225271 B 1 Jul 1985, 5 pp. (Czechoslovakia) CODEN: CZXXA9. CLASS: IC: C07C101-08. APPLICATION: CS 82-1600 9 Mar 1982. DOCUMENT TYPE: Patent CA Section: 34 (Amino Acids, Peptides, and Proteins) Requisite conditions were studied for the hydrogenation of PhCH:C(NHAc)CO2H (I) and 3,4-MeO(AcO)C6H3CH:C(NHAc)CO2H over Rh complex catalysts. Thus, hydrogenation of 220 parts I in a 1:2 C6H6-EtOH mixt. contg. [Rh(C2H4)2]2Cl2 and chiral diphosphine (R,R)-I at 25° and 91 kPa gave 76 parts (R)-N-acetylphenylalanine of 99.5% optical purity. .

Adsorbents for aminoacylase purification

Adsorbents for aminoacylase purification. Yano, Shigeru; Kikuchi, Yoshiyuki (Central Glass Co., Ltd., Japan). Jpn. Kokai Tokkyo Koho JP 61242578 A2 28 Oct 1986 Showa, 4 pp. (Japan) CODEN: JKXXAF. CLASS: ICM: C12N009-80. ICA: B01D015-08; C12N009-00. APPLICATION: JP 85-82186 19 Apr 1985. DOCUMENT TYPE: Patent CA Section: 7 (Enzymes) A water-insol. carrier contg. N-acyl-D-phenylalanine [PhCH2CH(CO2H)NHCOR; R = H, Me, halo-substituted Me) bound to the carrier via the CO2H group is an adsorbent for the purifn. of aminoacylase. Thus, porous glass beads (120-200 mesh, av. pore size = 220 ?) were treated with 10% aminopropyltriethoxysilane at 75° and pH 5.4 for 2 h. The silylated glass beads were mixed with a soln. of N-acetyl-D-phenylalanine (1.8 g/70 mL) and to this was added 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide-HCl. The mixt. 58856-73-8 and 10172-89-1 are cas registry numbers of chemicals which are used as reagents here. was shaken at room temp. for 24 h to produce an adsorbent. For purifn., an aminoacylase sample was passed through a column contg. the adsorbent using 0.05 M phosphate buffer (pH 8.0) as eluent. The recovery was 88.8% and the specific activity increased from 1.86 to 11.0 units/mg. .