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1027-14-1

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Basic Information
CAS No.: 1027-14-1
Name: 2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide monohydrochloride
Article Data: 2
Molecular Structure:
Molecular Structure of 1027-14-1 (2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide monohydrochloride)
Formula: C15H24 N2 O . Cl H
Molecular Weight: 284.829
Synonyms: Acetamide,2-(diethylamino)-N-(2,4,6-trimethylphenyl)-, monohydrochloride (9CI);Acetanilide, 2-(diethylamino)-2',4',6'-trimethyl-, monohydrochloride (8CI);Acetanilide, 2-diethylamino-2',4',6'-trimethyl-, hydrochloride (6CI); Mesocain;Mesocaine; Trimecaine hydrochloride; Trimekain hydrochloride
EINECS: 213-836-8
Melting Point: 137-138℃ (acetone )
Boiling Point: 360.3 °C at 760 mmHg
Flash Point: 171.7 °C
Safety: Poison by intraperitoneal and subcutaneous routes. When heated to decomposition it emits very toxic fumes of NOx and HCl.
PSA: 35.83000
LogP: 4.34360
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  • Acetamide,2-(diethylamino)-N-(2,4,6-trimethylphenyl)-, hydrochloride (1:1)

  • Casno:

    1027-14-1

    Acetamide,2-(diethylamino)-N-(2,4,6-trimethylphenyl)-, hydrochloride (1:1)

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  • 2-(Diethylamino)-N-mesitylacetamide hydrochloride manufacture

  • Casno:

    1027-14-1

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  • Acetamide,2-(diethylamino)-N-(2,4,6-trimethylphenyl)-, hydrochloride (1:1)

  • Casno:

    1027-14-1

    Acetamide,2-(diethylamino)-N-(2,4,6-trimethylphenyl)-, hydrochloride (1:1)

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Chemistry

Empirical Formula: C15H25ClN2O
Molecular Weight: 284.8248 g/mol
EINECS: 213-836-8 
Flash Point: 171.7 °C
Enthalpy of Vaporization: 60.6 kJ/mol
Boiling Point: 360.3 °C at 760 mmHg
Vapour Pressure: 2.24E-05 mmHg at 25 °C
Structure of Trimecaine Monohydrochloride (CAS NO.1027-14-1):
                    
IUPAC Name of Trimecaine Monohydrochloride (CAS NO.1027-14-1): Diethyl-[2-oxo-2-(2,4,6-trimethylanilino)ethyl]azanium chloride
Product Categories of Trimecaine Monohydrochloride (CAS NO.1027-14-1): Drug / Therapeutic Agent

Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 172mg/kg (172mg/kg)   Acta Facultatis Pharmaceuticae, Universitatis Comenianae. Vol. 29, Pg. 81, 1976.
mouse LD50 intravenous 50mg/kg (50mg/kg) BEHAVIORAL: TREMOR
BEHAVIORAL: ATAXIA
LUNGS, THORAX, OR RESPIRATION: DYSPNEA		 Farmakologiya i Toksikologiya Vol. 25, Pg. 731, 1962.
mouse LD50 subcutaneous 295mg/kg (295mg/kg)   "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989Vol. 11, Pg. 1526, 1989.
rabbit LD50 intraperitoneal 95mg/kg (95mg/kg)   Drug Metabolism and Drug Interactions. Vol. 9, Pg. 321, 1991.
 

Safety Profile

Poison by intraperitoneal and subcutaneous routes. When heated to decomposition it emits very toxic fumes of NOx and HCl.

Specification

 Trimecaine Monohydrochloride ,its cas register number is 1027-14-1. It also can be called Mesocaine ; Acetanilide, 2-(diethylamino)-2',4',6'-trimethyl-, hydrochloride ; and 2-(Diethylamino)-N-(2,4,6-trimethylphenyl)acetamide monohydrochloride .

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