Detail of "1045-69-8"

MSDS Download
CAS Number:
1045-69-8
Name:
Androst-4-en-3-one,17-(acetyloxy)-, (17b)-
Superlist Name:
Testosterone acetate
Molecular Structure:
Formula:
C₂₁H₃₀O₃
Molecular Weight:
330.47
Synonyms:
Androst-4-en-17b-ol-3-one acetate;Androtest A;Deposteron;Farmatest;NSC 523836;Perandrone A;SKF 5647;Testosterone17-acetate;Testosterone,acetate (6CI,8CI);17-O-Acetyltestosterone;17b-Acetoxy-4-androsten-3-one;17b-Acetoxy-D4-androsten-3-one;17b-Acetoxyandrost-4-ene-3-one;17b-Acetoxytestosterone;17b-Hydroxyandrost-4-en-3-oneacetate;17b-Hydroxyandrost-4-en-3-one-17b-acetate;3-Oxoandrost-4-en-17b-yl acetate;4-Androsten-17b-ol-3-one 17-acetate;Aceto-sterandryl;Aceto-testoviron;Amolisin;
EINECS:
213-876-6
Density:
1.12 g/cm³
Melting Point:
139-141 °C
Boiling Point:
441.803 °C at 760 mmHg
Flash Point:
191.472 °C
Hazard Symbols:
T
Risk Codes:
45-22-63
Safety:
53-22-26-36 Details
Transport Information:
UN 2811 6.1/PG 2

Famous Chemical Enterprises

Livzon
Total
Shell
Dupont
Exxonmobil
Akzonobel
Basf
Bayer
BP

Other Products

All Suppliers

Supplier Location
Supplier Location
- China (Mainland)(24)
Business Type
Business Type
- Lab/Research institutions(1)
- Manufacturers(3)
- Trading Company(14)
Certificates
Certificates
- Production License(3)
- ISO(1)

Please post your buying leads>>

Display：

Manufacturer
Enterprise Authentication
Suppiers of more reward points first
New supplier

Please post your buying leads,so that our qualified suppliers will soon contact you!
*Required Fields

Reference

Comparative study of the skin absorption of androgens: Comparative study of the skin absorption of androgens. Fedorov, V. K.; Pershin, G. N.; Shashkina, L. F.; Liberman, M. D. (Vses. Nauchno-Issled. Khim.-Farm. Inst. im. Ordzhonikidze, Moscow, USSR). Khim.-Farm. Zh., 11(3), 63-6 (Russian) 1977. CODEN: KHFZAN. DOCUMENT TYPE: Journal CA Section: 2 (Hormone Pharmacology) Testosterone propionate (I propionate) [57-85-2] applied to rat skin had greater androgenic activity (increasing seminal vesicle and prostate wts.) than testosterone caproate [10312-45-5]; testosterone [58-22-0] and testosterone phenylpropionate [1255-49-8] were still less effective. The androgenic potency of i.m. administered testosterone esters decreased in the following order: testosterone propionate < testosterone isocaproate [15262-86-9] < testosterone phenylpropionate < testosterone acetate [1045-69-8] < testosterone enanthate [315-37-7] < testosterone < testosterone caproate. A math formula was derived relating skin-absorption capacity for these compds. based on i.m. results. Skin absorbability was related to lipophilicity, mol. wts., and mol. configuration.

High-affinity binding of substrate and effector ligands to testicular microsomal cytochrome P-450: High-affinity binding of substrate and effector ligands to testicular microsomal cytochrome P-450. Quinn, Patrick G.; Payne, Anita H. (Dep. Biol. Chem., Univ. Michigan, Ann Arbor, MI 48109-0278, USA). J. Steroid Biochem., 25(6), 943-9 (English) 1986. CODEN: JSTBBK. ISSN: 0022-4731. DOCUMENT TYPE: Journal CA Section: 2 (Mammalian Hormones) Section cross-reference(s): 7 The binding characteristics of substrate and effector ligands to mouse testicular microsomal cytochrome P 450 [9035-51-2] were investigated by difference spectroscopy. Progesterone [57-83-0] and 17a-hydroxyprogesterone [68-96-2], the enzyme's substrates, bound stoichiometrically to microsomal P 450 with unusually high affinity (Kd = 23-51 nM.). The binding affinities of inhibitory effector ligands were detd. in competition expts. with the substrates. Several steroids which have varying effects on damage of P 450 in cultured Leydig cells inhibited substrate binding similarly (KdI = 3.8-12.8 mM). Aminoglutethimide did not inhibit substrate binding. Apparently, steroid binding to P 450 is necessary but not sufficient to increase O free-radical damage of the testicular microsomal P 450. Testosterone acetate [1045-69-8], which diminishes P 450 loss in Leydig cell cultures, was also bound stoichiometrically with high affinity (Kd = 17 nM) and produced a unique spectra, with max. at 408 nm, an isosbestic point at 418 nm and min. at 428 nm. Therefore, the protection of P 450 in cultured Leydig cells probably results from binding of testosterone acetate at the active site of P 450.

Detail of "1045-69-8"

Androst-4-en-3-one,17-(acetyloxy)-, (17b)-

Famous Chemical Enterprises

Related products

Other Products

Supplier Location

Business Type

Certificates

CAS No.1045-69-8 Testosterone acetate

CAS No.1045-69-8 Testosterone acetate

CAS No.1045-69-8 Testosterone acetate

CAS No.1045-69-8 Testosterone acetate

CAS No.1045-69-8 Testosterone acetate

CAS No.1045-69-8 Testosterone acetate

CAS No.1045-69-8 Testosterone acetate

CAS No.1045-69-8 Testosterone acetate

CAS No.1045-69-8 Testosterone acetate

CAS No.1045-69-8 Testosterone acetate

CAS No.1045-69-8 Testosterone acetate

CAS No.1045-69-8 Testosterone acetate

CAS No.1045-69-8 Testosterone acetate

CAS No.1045-69-8 Testosterone acetate

CAS No.1045-69-8 Testosterone acetate

CAS No.1045-69-8 Testosterone acetate

CAS No.1045-69-8 Testosterone acetate

CAS No.1045-69-8 Testosterone acetate

CAS No.1045-69-8 Testosterone acetate

CAS No.1045-69-8 Testosterone acetate

CAS No.1045-69-8 Testosterone acetate

CAS No.1045-69-8 Testosterone acetate

CAS No.1045-69-8 Testosterone acetate

CAS No.1045-69-8 Testosterone acetate

Reference