Detail of "10597-89-4"

Reference

Pharmacological activity of bacterial peptidoglycan: the effect on temperature and sleep in the rat

Pharmacological activity of bacterial peptidoglycan: the effect on temperature and sleep in the rat. Masek, K.; Kadlecova, O.; Petrovicky, P. (Inst. Pharmacol., Czech. Acad. Sci., Prague, Czech.). Toxicon, Volume Date 1976, Suppl. 1(Toxins: Anim., Plant Microb.), 991-1003 (English) 1978. CODEN: TOXIA6. ISSN: 0041-0101. DOCUMENT TYPE: Journal CA Section: 4 (Toxicology) A basic structure of cell wall of gram-pos. bacteria peptidoglycan was investigated for pyrogenic potency and for its effect on sleep. Both effects seem to be related to the brain stem and the results of small electrolytic lesions as well as the results of study of 5-hydroxytryptamine [50-67-9] turnover suggest the involvement of 5-hydroxytryptaminergic structures. Expts. with inhibitors of prostaglandin synthesis (salicylates and indomethacin) suggest the possibility of a participation of prostaglandins in the pyretic effects. The comparative study with synthetically prepd. peptidoglycan subunit peptides and N-acetylmuramyl peptide revealed that the minimal structure required for the pyrogenic effect is a peptide subunit while the introduction of N-acetylmuramic acid [10597-89-4] is necessary to observe the effect on sleep.

Lysozyme-sensitive bioemulsifier for immiscible organophosphorus pesticides

Lysozyme-sensitive bioemulsifier for immiscible organophosphorus pesticides. Patel, Mukul N.; Gopinathan, Karumathil P. (Microbiol. Cell Biol. Lab., Indian Inst. Sci., Bangalore 560 012, India). Appl. Environ. Microbiol., 52(5), 1224-6 (English) 1986. CODEN: AEMIDF. ISSN: 0099-2240. DOCUMENT TYPE: Journal CA Section: 5 (Agrochemical Bioregulators) Section cross-reference(s): 10 Two Bacillus strains capable of emulsifying immiscible organophosphorus pesticides were isolated by enrichment culture. The emulsifying factor produced by Bacillus strain FE-2 has a high mol. wt., is lysozyme [9001-63-2]-sensitive and thermostable, and can be pptd.There are some commonly used reagents with their cas registry numbers 9001-86-9 and 9036-06-0 in this article. with TLA or (NH4)2SO4; it may be a glycolipopeptide. It is specific for immiscible organophosphorus pesticides and is secreted during growth in the presence of such pesticides. The complete loss of emulsifying activity on treatment with lysozyme indicates that the carbohydrate moiety may contain (b1?4)-linked N-acetylglucosamine [7512-17-6] and N-acetylmuramic acid [10597-89-4]. These conclusions were confirmed by (1) inhibition of emulsifying activity in the presence of wheat germ agglutinin, (2) prevention of such inhibition in the presence of free N-acetylglucosamine, and (3) loss of a specific band in lysozyme-treated supernatant compared with untreated supernatant after electrophoresis on a 7.5% polyacrylamide gel and the presence of emulsifying activity in the corresponding band of untreated supernatant. .