CAS No.109-54-6,3-Chloro-1-(N,N-dimethyl)propylamine Suppliers

Detail of "109-54-6"

CAS Number:

109-54-6

Name:

3-Chloro-1-(N,N-dimethyl)propylamine

Molecular Structure:

Formula:

C₅H₁₂ClN

Molecular Weight:

121.61

Synonyms:

Propylamine,3-chloro-N,N-dimethyl- (6CI,7CI,8CI);(3-Chloropropyl)dimethylamine;1-Chloro-3-(dimethylamino)propane;1-Dimethylamino-3-chloropropane;3-(Dimethylamino)-1-propyl chloride;3-(Dimethylamino)propyl chloride;3-(N,N-Dimethylamino)propyl chloride;3-Chloro-1-(dimethylamino)propane;3-Chloro-N,N-dimethylpropanamine;3-Dimethylamino-1-chloropropane;3-Dimethylaminopropan-1-yl chloride;Dimethyl(3-chloropropyl)amine;N,N-Dimethyl-3-chloro-1-propanamine;N,N-Dimethyl-3-chloropropanamine;N-(3-Chloropropyl)-N,N-dimethylamine;g-Chloropropyldimethylamine;g-Dimethylaminopropyl chloride;

EINECS:

203-679-3

Density:

0.937 g/cm³

Boiling Point:

130.7 °C at 760 mmHg

Flash Point:

32.8 °C

Reference

Dihydromorphanthridin-11-ol derivative-containing drugs with antidepressive activity: Dihydromorphanthridin-11-ol derivative-containing drugs with antidepressive activity. (Richardson-Merrell Inc., USA). Neth. Appl. NL 7606064 6 Dec 1977, 15 pp. (Dutch). (Netherlands). CODEN: NAXXAN. CLASS: IC: A61K031-395. APPLICATION: NL 76-6064 4 Jun 1976. DOCUMENT TYPE: Patent CA Section: 1 (Pharmacodynamics) Section cross-reference(s): 27 A new class of antidepressants has the structure I(Z = N:CR or NHCHR: R,R1, R2 = H or C1-4 alkyl; R3 = NR4R5 or N-contg. heterocycle; X,Y = H, OH, halogen, alkoxyalkyl, thioalkyl, CF3, or SO2NR6R7). These compds. and their salts are equal to a >10-fold more potent antidepressant than imipramine, and have low toxicity with no anticolinergic activity or other side effects. For example, 48.6 g dimethylaminopropyl chloride [109-54-6] was converted to the Grignard reagent and combined with 20.9 g 5,6-dihydromorphanthridin-11-one [3297-48-1] in THF. After two h under reflux, the soln. was cooled in ice and 75 mL satd. NH4Cl soln. was added. The ppt. was removed and the filtrate was evapd. to dryness to yield 11-(3-dimethylaminopropyl)-5,6-dihydromorphanthridin-11-ol [64063-40-7] which was crystd. from MeCOCN.

Preparation of 3-dimethylaminopropylmagnesium chloride: Preparation of 3-dimethylaminopropylmagnesium chloride. Puncochar, Ludvik; Mayer, Jiri; Protiva, Miroslav (Czech.). Czech. CS 232509 B1 15 Aug 1986, 7 pp. (Czechoslovakia) CODEN: CZXXA9. CLASS: ICM: C07F003-02. APPLICATION: CS 83-3593 20 May 1983. DOCUMENT TYPE: Patent CA Section: 29 (Organometallic and Organometalloidal Compounds) Highly pure Me2N(CH2)3MgCl is prepd.In this article, certain chemicals are used. One of their cas registry numbers is 109-54-6 by liberating Me2N(CH2)3Cl from the hydrochloride with aq. NaOH, extg. the base into petroleum ether, washing the ext., removing water by azeotropic distn., and boiling the petroleum ether soln. with powd. Mg, optionally in a mixt. with PhMe. .

Detail of "109-54-6"

3-Chloro-1-(N,N-dimethyl)propylamine

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CAS No.109-54-6 3-Chloro-1-(N,N-dimethyl)propylamine

CAS No.109-54-6 3-Chloro-1-(N,N-dimethyl)propylamine

CAS No.109-54-6 3-Chloro-1-(N,N-dimethyl)propylamine

CAS No.109-54-6 3-Chloro-1-(N,N-dimethyl)propylamine

CAS No.109-54-6 3-Chloro-1-(N,N-dimethyl)propylamine

CAS No.109-54-6 3-Chloro-1-(N,N-dimethyl)propylamine

CAS No.109-54-6 3-Chloro-1-(N,N-dimethyl)propylamine

CAS No.109-54-6 3-Chloro-1-(N,N-dimethyl)propylamine

CAS No.109-54-6 3-Chloro-1-(N,N-dimethyl)propylamine

CAS No.109-54-6 3-Chloro-1-(N,N-dimethyl)propylamine

CAS No.109-54-6 3-Chloro-1-(N,N-dimethyl)propylamine

CAS No.109-54-6 3-Chloro-1-(N,N-dimethyl)propylamine

CAS No.109-54-6 3-Chloro-1-(N,N-dimethyl)propylamine

CAS No.109-54-6 3-Chloro-1-(N,N-dimethyl)propylamine

Reference