Reference

Antimicrobial activity of different series of lignin carbamates

Antimicrobial activity of different series of lignin carbamates. Mohamed, Zeinat K.; Nagaty, Ahmed; Mansour, Olftat Y.; Nagieb, Zeinat A. (Cell. Paper Lab., Natl. Res. Cent., Giza, Egypt). Egypt.Some commonly used reagents like 109-90-0 and 110-78-1 are used in this experiment. J. Microbiol., 18(1-2), 179-90 (English) 1983. CODEN: EJMBA2. ISSN: 0301-8172. DOCUMENT TYPE: Journal CA Section: 10 (Microbial Biochemistry) Carbamate complexes were prepd. by the fusion of alkali lignin with isocyanates at high temps. and in the absence of catalysts. The order of reactivity of the different isocyanates towards the reaction was Ph isocyanate > Pr isocyanate or cyclohexyl isocyanate > Et isocyanate. This reactivity is indicated by the percent yield of the carbamates and the no. of N atoms inserted in the carbamate mols. All the compds. exhibited antimicrobial activity against bacteria and slight activity against yeasts and fungi. The Ph- and Et-lignin carbamates were much more potent than the Pr- and cyclohexyl-lignin carbamates. There was no relation between either the elemental compn. or the mol. formula of these complexes and their antimicrobial activity. Max. absorption of the electronic spectra occurs at 325 mm for all complexes. IR spectra revealed some similarities in the bands between the different kinds of lignin carbamates. The difference in the antimicrobial activity of the Ph- and Et-lignin carbamates on the one hand, and the Pr- and cyclohexyl-lignin carbamates on the other hand, is attributed to the presence of 1:2:4 aroms. together with 1:2 and 1:4 aroms. .

23-O-Substituted carbamoyl-23-demycinosyldesmycosin

23-O-Substituted carbamoyl-23-demycinosyldesmycosin. Fujiwara, Tatsuro; Ohta, Kazuyo; Honda, Eiichi; Hirano, Takao; Sakakibara, Hideo (Toyo Jozo Co., Ltd. , Japan). Ger. Offen. DE 3301959 A1 4 Aug 1983, 49 pp. (German). (Germany).Several reagents with their cas registry numbers 110-78-1 and 87775-05-1 are used here. CODEN: GWXXBX. CLASS: IC: C07H017-08; A61K031-71; A23K001-17. APPLICATION: DE 83-3301959 20 Jan 1983. PRIORITY: JP 82-7820 20 Jan 1982; JP 82-78896 10 May 1982; JP 82-78897 10 May 1982. DOCUMENT TYPE: Patent CA Section: 33 (Carbohydrates) Section cross-reference(s): 1 The title compds. I (X = O, S; R = alkyl, alkoxycarbonylakyl, Ph, substituted Ph, aralkyl; R1 = H, alkyl; NRR1 = heterocyclyl; R2 = H, OH) were prepd. Thus, 23-demycinosyldesmycosin was 2',4'-diacetylated, treated with 2,5-Cl2C6H3NCO, and deacylated to give I (X = O, R = 2,5-Cl2C6H3, R1 = H, R2 = OH) which had a min. inhibitory concn. against Staphylococcus aureus ATCC 6538P 0.1 mg/mL. .