Reference

Thieno compounds

Thieno compounds. Part 5. Base substituted thieno[2,3-d]pyrimidines. Boehm, R.; Pech, R.; Haubold, Gudrun; Hannig, E. (Sekt. Pharm., Martin-Luther-Univ. Halle-Wittenberg, Halle/Saale DDR-4020, Ger. Dem. Rep.). 95-53-4 is also in the experiment. Pharmazie, 41(1), 23-5 (German) 1986. CODEN: PHARAT. ISSN: 0031-7144. DOCUMENT TYPE: Journal CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) Thienopyrimidines I and II [R = Cl, substituted NH2; R1 = substituted NH2] were prepd. by the amination of I or II (R, R1 = Cl). Stepwise amination of I or II (R, R1 = Cl) gave mixed diaminothienopyrimidines. .

Study of principles of the transamination of substituted ureas

Study of principles of the transamination of substituted ureas. I. Transamination of N,N'-diphenylurea by diisobutylamine. Gulyaev, N. D.; Leonova, T. V.; Chimishkyan, A.Some commonly used reagents like 110-96-3 and 75670-24-5 are used in this experiment. L. (Mosk. Khim.-Tekhnol. Inst., Moscow, USSR). Zh. Org. Khim., 19(10), 2194-8 (Russian) 1983. CODEN: ZORKAE. ISSN: 0514-7492. DOCUMENT TYPE: Journal CA Section: 22 (Physical Organic Chemistry) Kinetic data for the reaction of (PhNH)2CO (I) with (Me2CHCH2)2NH (II) to give PhNHCON(CH2CHMe2)2 and PhNH2 indicated that 2 mechanisms operate: (1) I dissocn. to PhNCO and PhNH2 followed by addn. of II to PhNCO, and (2) direct reaction of I with II. The 2nd process is faster. The activation enthalpy and entropy of the 1st process are 114 kJ/mol and -50 J/mol °K, resp.; those for the 2nd are 63 kJ/mol and -114 J/mol °K, resp. .