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CAS No.: | 11028-71-0 |
---|---|
Name: | CONCANAVALIN A TYPE III |
Molecular Structure: | |
Formula: | Unspecified |
Molecular Weight: | 0 |
Synonyms: | Con A;Concanavaline A;Lectins, concanavalins A; |
EINECS: | 234-258-2 |
Flash Point: | 39 °C |
Solubility: | PBS: 5 mg/mL, slightly hazy |
Hazard Symbols: | Xn |
Risk Codes: | 10 |
Safety: | 36 |
Transport Information: | UN 1170 3/PG 3 |
PSA: | 0.00000 |
LogP: | 0.00000 |
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The CAS registry number of Concanavalin A is 11028-71-0. It is a lectin (carbohydrate-binding protein) originally extracted from the jack-bean. And it is the first lectin to be available on a commercial basis. In addition, it is a plant mitogen, and is known for its ability to stimulate mouse T-cell subsets giving rise to four functionally distinct T cell populations.
Uses of Concanavalin A: it is widely used in biology and biochemistry to characterize glycoproteins and other sugar-containing entities on the surface of various cells. And it is used to purify glycosylated macromolecules in lectin affinity chromatography. Moreover, it is useful in applications requiring solid-phase immobilization of glycoenzymes.
When you are using this chemical, please be cautious about it as the following:
This chemical is flammable. During using it, wear suitable protective clothing.
The toxicity data is as follows:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
mouse | LD50 | intraperitoneal | 41500ug/kg (41.5mg/kg) | National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. Vol. JAN1986, | |
mouse | LD50 | intravenous | 50mg/kg (50mg/kg) | Arzneimittel-Forschung. Drug Research. Vol. 30, Pg. 759, 1980. | |
rabbit | LDLo | intravenous | 5385ug/kg (5.385mg/kg) | Journal of Bacteriology. Vol. 32, Pg. 227, 1936. |