Detail of "1107-99-9"

CAS Number:
1107-99-9
Name:
Pregna-1,4-diene-3,20-dione,21-(2,2-dimethyl-1-oxopropoxy)-11,17-dihydroxy-, (11b)-
Superlist Name:
Prednisolone 21-trimethylacetate
Molecular Structure:
Formula:
C26H36 O6
Molecular Weight:
444.56
Synonyms:
Pregna-1,4-diene-3,20-dione,11b,17,21-trihydroxy-, 21-pivalate(6CI,7CI,8CI); 11b,17a-Dihydroxy-21-pivaloyloxypregna-1,4-diene-3,20-dione;Mecortolon; PTMA; Prednisolone 21-pivalate; Prednisolone 21-trimethylacetate;Prednisolone pivalate; Prednisolone trimethylacetate; Ultracortenol;Ultracorterenol; Vecortenol
EINECS:
214-172-1
Density:
1.23 g/cm³
Boiling Point:
597.3 °C at 760 mmHg
Flash Point:
196.7 °C

Supplier Location
Supplier Location
- China (Mainland)(2)
Business Type
Business Type
- Lab/Research institutions(1)
- Manufacturers(0)
- Trading Company(1)
Certificates
Certificates
- ISO (0)
- Production License (0)

Display：

Molecular Weight 444.6 Molecular Formula C26H366O6

262 Integral
262

Tel:+86-22-23697098

Address:Boke Building,No.100 Fukang Road,Nankai District,Tianjin,China

600 Integral
600

Tel:86-22-23709100, 23709200

Address:Hi-Tech Building A, Room507-511,Huatian Road,Huayuan Industry Park, Tianjin 300384, China

Please post your buying leads,so that our qualified suppliers will soon contact you!
*Required Fields

A thermographic assessment of three intra-articular prednisolone analogs given in rheumatoid synovitis: A thermographic assessment of three intra-articular prednisolone analogs given in rheumatoid synovitis. Esselinckx, W.; Bacon, P. A.; Ring, E. F. J.; Crooke, D.; Collins, A. J.; Demottaz, D. (Arthritis Rheum. Counc. Res. Group, R. Natl. Hosp. Rheum. Dis., Bath, Engl.). Br. J. Clin. Pharmacol., 5(5), 447-51 (English) 1978. CODEN: BCPHBM. ISSN: 0306-5251. DOCUMENT TYPE: Journal CA Section: 2 (Hormone Pharmacology) Prednisolone acetate (I acetate) [52-21-1], prednisolone pivalate [1107-99-9], and prednisolone tert-butylacetate [7681-14-3] injected into the knee joints of patients with rheumatoid arthritis at 50 mg produced rapid suppression of inflammation. The duration and extent of the antiinflammatory effects of the analogs was dependent on their soly., the acetate being the most sol. had the shortest duration of action, whereas the tert-butylacetate was the least sol. and had the longest duration of action. Increasing the dose to 100 mg increased the antiinflammatory effect only with the sol. acetate prepn.

Application of Curvularia sp: Application of Curvularia sp. to the hydrolysis of steroid pivalates. Kruszewska, Hanna; Chmielowiec, Urszula; Uszycka-Horawa, Teresa ( Pharmaceutical Research Institute, Warsaw 01-793, Pol.). Farmaco, 51(12), 809-810 (English) 1996 Societa Chimica Italiana. CODEN: FRMCE8. DOCUMENT TYPE: Journal CA Section: 16 (Fermentation and Bioindustrial Chemistry) As glucocorticoids have alkali-sensitive hydroxyacetylic side chain, conventional methods of removing of 21-pivalates groups are risky. 51192-49-5 and 1107-99-9 are also in the experiment. In this paper we described the hydrolysis of pivalates of some glucocorticoids by fungi imperfecti: Curvularia lunata, Curvularia tuberculata, Cylindrocladium simplex Meyer and Cunninghamella elegans. The highest yield of hydrolysis was found in the case of hydrocortisone and prednisolone pivalates with Curvularia lunata and Curvularia tuberculata. The other two tested enzymes gave in all studied cases null or extremely poor results. .