CAS No.11116-32-8,Bleomycin A5 Suppliers

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Basic Information

Molecular Structure:
CAS No.:	11116-32-8
Name:	Bleomycin A5

Formula:	C57H89 N19 O21 S2
Molecular Weight:	1423.73
Synonyms:	Bleomycetin;Bleomycin A5; NSC 350895; Pingyangmycin A5; Zhengguangmycin A5
EINECS:	234-357-0
Density:	1.56g/cm³
Boiling Point:	°Cat760mmHg
Flash Point:	°C
Safety:	Poison by intraperitoneal, intravenous, intramuscular, and subcutaneous routes. Moderately toxic by ingestion. Human systemic effects by an unspecified route: nausea or vomiting, dyspnea, and fever. Mutation data reported. When heated to decomposition it emits very toxic fumes of SO_x and NO_x. See other bleomycin entries.
PSA:	721.60000
LogP:	-1.43400

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Chemistry

Chemical Name: Bleomycin A5
IUPAC NAME: [2-[2-[2-[[6-amino-2-[3-amino-1-[(2,3-diamino-3-oxopropyl)amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[[5-[[1-[2-[4-[4-[3-(4-aminobutylamino)propylcarbamoyl]-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]ethylamino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-hydroxy-4-methyl-5-oxopentan-2-yl]amino]-1-(1H-imidazol-5-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate
CAS No.: 11116-32-8
EINECS: 234-357-0
Molecular Formula: C₅₇H₈₉N₁₉O₂₁S₂
Molecular Weight: 1440.56 g/mol
Density: 1.56 g/cm³
The chemical synonymous of Bleomycin A5 (CAS No.11116-32-8) are Bleomycinamide, N1-[3-[(4-Aminobutyl)Amino]Propyl]- ; Bleomycetin ; Bleomycin A5 ; N1-(3-((4-Aminobutyl)Amino)Propyl)Bleomycinamide ; Pingyangmycin A5 ; Zhengguanmycin A5

Toxicity Data With Reference

1.	cyt-ham:ovr 400 µg/L	HKXUDL Huanjing Kexue Xuebao. Environmental Sciences Journal. 3 (1983),78.
2.	sce-ham:ovr 400 µg/L	HKXUDL Huanjing Kexue Xuebao. Environmental Sciences Journal. 3 (1983),78.
3.	unr-hmn TDLo:192 mg/kg:GIT,PUL,MET	ANTBAL Antibiotiki. 28 (8)(1983),632.
4.	ipr-rat LD50:117 mg/kg	ANTBAL Antibiotiki. 24 (5)(1979),363.
5.	ivn-rat LD50:100 mg/kg	ANTBAL Antibiotiki. 24 (5)(1979),363.
6.	ims-rat LD50:102 mg/kg	ANTBAL Antibiotiki. 24 (5)(1979),363.
7.	orl-mus LD50:840 mg/kg	ANTBAL Antibiotiki. 24 (5)(1979),363.
8.	ipr-mus LD50:88 mg/kg	ANTBAL Antibiotiki. 24 (5)(1979),363.
9.	scu-mus LD50:77 mg/kg	ANTBAL Antibiotiki. 24 (5)(1979),363.
10.	ivn-mus LD50:61,500 µg/kg	ANTBAL Antibiotiki. 24 (5)(1979),363.

Safety Profile

Poison by intraperitoneal, intravenous, intramuscular, and subcutaneous routes. Moderately toxic by ingestion. Human systemic effects by an unspecified route: nausea or vomiting, dyspnea, and fever. Mutation data reported. When heated to decomposition it emits very toxic fumes of SO_x and NO_x. See other bleomycin entries.