Detail of "112-37-8"

Reference

Levels of short-chain fatty acids and of abscisic acid in water-stressed and non-stressed leaves and their effects on stomata in epidermal strips and excised leaves

Levels of short-chain fatty acids and of abscisic acid in water-stressed and non-stressed leaves and their effects on stomata in epidermal strips and excised leaves. Willmer, C. M.; Don, R.; Parker, W. (Dep. Biol., Univ. Stirling, Stirling, Scot.). Planta, 139(3), 281-7 (English) 1978. CODEN: PLANAB. ISSN: 0032-0935. DOCUMENT TYPE: Journal CA Section: 11 (Plant Biochemistry) Straight-chain satd. fatty acids (C6-C11) and abscisic acid (I) accumulate in the leaves of Phaseolus vulgaris and Hordeum vulgare under water stress. I and certain of the fatty acids, particularly decanoic and undecanoic acid, can inhibit stomatal opening and cause stomatal closure in epidermal strips of Commelina communis, depending on the incubating medium used. I (10-4M) inhibits opening in media contg. either high or relatively low concns. of KCl but causes closure only in the latter medium. The fatty acids (at 10-4M) prevent opening in both media while significant closure of open stomato was caused only by undecanoic acid in both media and, addnl., by decanoic acid in the low-KCl medium. Formic acid (10-4M) also caused stomatal closure and prevented opening to significant extents in the low-KCl medium. The efficacy of undecanoic acid in causing 50% inhibition of opening is about 3X lower than that of I. At a concn. of 10-3M, nonanoic, decanoic, and particularly undecanoic acid and all-trans-farnesol cause increased cell leakage in Beta vulgaris root tissue. Undecanoic acid (10-4M) also causes some loss of guard cell integrity in C. communis within 1.5 h of treatment. I (10-4M) reduces transpiration rates in barley and C. cummunis leaves when applied via the transpiration stream but decanoic and undecanoic acids did not have this effect. Transpiration was not affected when I or the fatty acids were applied to the leaf surfaces.

Modification of adipic acid crystals: influence of growth in the presence of fatty acid additives on crystal properties

Modification of adipic acid crystals: influence of growth in the presence of fatty acid additives on crystal properties. Chow, K. Y.; Go, J.; Mehdizadeh, M.; Grant, D. J. W. (Fac. Pharm., Univ. Toronto, Toronto, ON M5S 1A1, Can.). Int. J. Pharm., 20(1-2), 3-24 (English) 1984. CODEN: IJPHDE. ISSN: 0378-5173. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) Section cross-reference(s): 75 When adipic acid [124-04-9] is crystd. from water in the presence of a low concn. of an n-alkanoic acid, the additive is incorporated into the crystals and the crystal habit is changed. The following properties of harvested crystals grown in the presence of various concns. of hexanoic (C6) [142-62-1], octanoic (C8) [124-07-2] or undecanoic acid (C11) [112-37-8] were studied: dissoln. rate (DR) and enthalpy of soln. (DHs) in water, enthalpy of fusion (DHf), m.p. (Tm), d., sp. surface area (A) and SEM. Increasing concns. of C6 (0-5380 mmol×dm-3) or C11 (0-67.1 mmol×dm-3) caused increasing uptake of additive and pitting of the crystal surface under SEM, while DR and A of a defined sieve fraction increased and then decreased, whereas DHs and DHfdecreased to min. and then increased. In general, the changes in Tm and entropy of fusion (DSf) paralleled the changes in DHf. C6 caused negligible changes in d. whereas C11 significantly reduced d. suggesting lattice expansion (0-0.8%). Various sieve fractions covering the range <75 mm to 850 mm showed negligible differences in DHf, DHs, Tm and d. C8 (0-139 mmol×dm-3) elicited behavior similar to that produced by C6 and C11, except that it reduced DR and increased d. (<0.8%). X-ray powder diffraction of all cryst. samples failed to detect any changes in lattice dimensions (<0.5%). Overall, DR did not exactly parallel A or SEM on the one hand, nor DHf, DHs, Tm or d. on the other hand, implying that DR depends on both the surface and bulk properties of the modified crystals. Growth of drug crystals in the presence of low concns. of non-toxic additives can be used to control dissoln. rate and crystal energy.