Reference

Use of sodium borohydride

Use of sodium borohydride.Some chemicals with cas registry numbers like 1731-84-6 and 1129-35-7 are also used. Kikukawa, Yasuo (Japan ). Japan. Kokai JP 51105001 17 Sep 1976 Showa,3 pp. (Japanese). (Japan). CODEN: JKXXAF. CLASS: IC: C07B001-00. APPLICATION: JP 75-29243 11 Mar 1975. DOCUMENT TYPE: Patent CA Section: 25 (Noncondensed Aromatic Compounds) Section cross-reference(s): 23 Treatment of NaBH4 with secondary amides RCONHR1 (R = alkyl, aryl; R1 = aryl) gave a reagent which reduced esters and ketones to the corresponding alcs. Thus, a mixt. of 990 mg PhCONHPh and 285 mg NaBH4 in .alpha.-picoline was heated 100 min at 40.degree., 860 mg Me n-nonanoate added, and the mixt. allowed to react 3 hr to give 627 mg n-nonyl alc. 4-HOCH2C6H4CONMe2, 4-HOCH2C6H4CN, PhCH2CH2OH, and PhCH2CH2CH(OH)Me were similarly prepd. from 4-MeO2CC6H4CONMe2, 4-MeO2CC6H4CN, PhCH2CO2Me, and PhCH2CH2COMe, resp. .

Bifunctional molecules that receive two electrons sequentially and reversibly through only one of their two reducible groups

Bifunctional molecules that receive two electrons sequentially and reversibly through only one of their two reducible groups. Zheng, Zi-Rong; Evans, Dennis H. (Department of Chemistry and Biochemistry, University of Delaware, Newark, DE 19706, USA). Journal of Electroanalytical Chemistry, 558, 99-107 (English) 2003 Elsevier Science B.V. CODEN: JECHES. DOCUMENT TYPE: Journal CA Section: 72 (Electrochemistry) Section cross-reference(s): 22 The electrochem. redn. mechanism of 4 bifunctional mols. [1,4-dimethyl-4-nitropentyl p-cyanobenzoate (2), cis-3-(1-methyl-1-nitroethyl)cyclopentyl p-cyanobenzoate (5), (3b,17b)-17-(4-methyl-4-nitro-1-oxopentyl)androst-5-en-3-yl p-cyanobenzoate (6), 2-methyl-2-nitropropyl p-cyanobenzoate (7)] was studied. Each of these compds. contains a kinetically fast electron-accepting group (p-cyanobenzoate function) and a kinetically slow electron-accepting group (2-nitroprop-2-yl), but each of these groups has an almost identical formal potential for redn. to the radical anion.Several substances with their cas registry numbers 4604-49-3 and 1129-35-7 may be metioned in this study. Compds. 2, 5 and 6 are reduced in the following pathway: (1) initial introduction of an electron into the fast end; (2) intramol. electron transfer from the fast to the slow end and (3) introduction of the 2nd electron into the fast end. For 2 and 5, the rate of the intramol. electron transfer reaction is too fast to measure, its rate const. exceeding 106 s-1. However, for 6, which features a long steroidal group that separates the fast and slow ends, the rate const. was of the order of 103 s-1 at 298 K and the effect of the slower intramol. electron transfer is clearly evident in the cyclic voltammograms. The redn. of 7 is complicated by a relatively rapid double cleavage reaction occurring at the state of the diradical dianion. .