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Detail of "114-07-8"

  • CAS Number:
  • 114-07-8
  • Name:
  • Erythromycin

  • Molecular Structure:
  • Formula:
  • C37H67NO13
  • Molecular Weight:
  • 733.93
  • Deleted CAS:
  • 374700-25-1
  • Synonyms:
  • Erythromycin A;Erymax;Pentadecanoic acid, 3-[(2, 6-dideoxy-3-C-methyl-3-O-methyl-.alpha.-L-ribo-hexopyranosyl)oxy]- 6,11,12,13-tetrahydroxy-2,4,6,8,10,12-hexamethyl-9-oxo-5-[[3,4, 6-trideoxy-3-(dimethylamino)-.beta.-D-xylo-hexopyranosyl]oxy]-, .mu.-lactone, [2R-(2R*,3S*,4S*,5R*,6R*,8R*,10R*,11R*,12S*,13S*)]-;Taimoxin-F;EM;Abomacetin;Abboticin;Erythro;Kesso-Mycin;Erythromid;Erycin;Propiocine;Ilotycin;Prestwick_205;6-(4-dimethylamino-3-hydroxy-6-methyl-oxan-2-yl)oxy-14-ethyl-7,12,13-trihydroxy-4-(5-hydroxy-4-methoxy-4,6-dimethyl-oxan-2-yl)oxy-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione;Oxacyclotetradecane-2,10-dione, 4-[(2, 6-dideoxy-3-C-methyl-3-O-methyl-.alpha.-L-ribo-hexopyranosyl)oxy]- 14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-6-[[3,4, 6-trideoxy-3-(dimethylamino)-.beta.-D-xylo-hexopyranosyl]oxy]-, [2R-(2R*,3S*,4S*,5R*,6R*,8R*,10R*,11R*,12S*,13S*)]-;
  • EINECS:
  • 204-040-1
  • Density:
  • 1.209 g/cm3
  • Melting Point:
  • 138-140 °C
  • Boiling Point:
  • 818.401 °C at 760 mmHg
  • Flash Point:
  • 448.753 °C
  • Solubility:
  • soluble in ethanol, methanol and chloroform, insoluble in water
  • Appearance:
  • white to off white crystalline powder
  • Hazard Symbols:
  • HarmfulXn,IrritantXi
  • Risk Codes:
  • 42/43-36/37/38
  • Safety:
  • 45-37-24-36-26 Details

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CAS No.114-07-8 ErythromycinCompetitive Product

Assay:96%~102%  Appearance:Colorless to...  Package:25kg/barrel

Usage:Erythromycin Stearate belongs to macrolide antibiotics, The antibacterial spectrum is similar with the penicillin, And to the mycoplasma, the chlamydia, Rickettsia and so on and the regiment fungus has the antibacterial function Specification:CP2005; USP27; BP2005; EP5.0

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CAS No.114-07-8 ErythromycinCompetitive Product

Erythromycin manufacturer CP2005; USP27; BP2005; EP5.0 Erythromycin belongs to macrolide antibiotics. It is mainly used in the treatment of the infections of staphylococcus resistant to penicillin and also used in the patients with the infections of streptococcus and pneumoc

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Erythromycin Film-coated Tablets

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Erythromycin A

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ERYTHROMYCIN BASE

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CAS No.114-07-8 Erythromycin

1.Quick detail CAS No.: 114-07-8 Place of Origin: China (Mainland) Grade Standard: Medicine Grade Purity: 99% min Appearance: White or off white crystalline powd... Assay: Not less than 920u/mg 2.Package and delivery Packaging Detail: 20KG/Drum Delivery Detail Within 7

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Erythromycin is a macrolide antibiotic that has an antimicrobial spectrum similar to or slightly wider than that of penicillin (IC50=1.5 μg/ml).

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IP / BP / USP / EP

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Reference

Study on the relation between the crystal forms of erythromycin lactate and their stability
Study on the relation between the crystal forms of erythromycin lactate and their stability. Bai, Fengqing; Zhang, Hanru; Wang, Lian (Liaoning Prov. Inst. Drug Control, Peop. Rep. China). Yaowu Fenxi Zazhi, 4(1), 4-8 (Chinese) 1984. CODEN: YFZADL. ISSN: 0254-1793. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) Erythromycin lactate (I lactate) [41033-54-9] was freeze dried to produce a type B crystal form and spray dried to produce a type A crystal form. They showed different IR and X-ray diffraction spectra. The type A crystal transformed to the type B crystal after treatment with anhyd. EtOH, and type B crystal transformed to the type A crystal after recrystn. with anhyd. EtOH-petroleum ether or drying at 105°. Anal. by TLC and the potency assay (Chinese Pharmacopeia, 1977) indicated that the type B crystal was more stable than the type A crystal to an accelerated degrdn. test at 60° for 30 days. The potency of the treated B crystal was decreased by 2.3-7.6% but that of the treated A crystal by 7.In this experiment, several chemicals are used like 41033-54-9 0-22.1%. .
Erythromycin salts showing a combined therapeutic activity and pharmaceutical formulations containing them
Erythromycin salts showing a combined therapeutic activity and pharmaceutical formulations containing them. Casini, Giovanni (Nuovo Consorzio Sanitario Nazionale, Italy). Eur. Pat. Appl. EP 96013 A1 7 Dec 1983, 18 pp. DESIGNATED STATES: R: AT, BE, CH, DE, FR, GB, LI, LU, NL, SE. (English). (European Patent Organization). CODEN: EPXXDW.In this article, certain chemicals are used. Some of their cas registry numbers are 89301-84-8 and 89265-49-6 CLASS: IC: C07H017-08; A61K031-70; C07C149-23. APPLICATION: EP 83-830098 18 May 1983. PRIORITY: IT 82-48539 28 May 1982. DOCUMENT TYPE: Patent CA Section: 33 (Carbohydrates) Section cross-reference(s): 10, 63 Salts of erythromycin or erythromycin 2'-propanoate (ester), with acetylsalicylic acid (I) and DL-a-mercaptopropionylglycine, with antibacterial, antipyretic, antiinflammatory, antirheumatic, mucolytic, and hepatoprotective activity, were prepd. Thus, 8.1 g propionylerythromycin (II) was treated with 1.8 g I in AcOEt to give 91% II-I salt. The salts prepd. showed in vitro antibacterial activity of the same order of magnitude as the parent antibiotics. .
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