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1165-39-5

Basic Information
CAS No.: 1165-39-5
Name: AFLATOXIN G1
Article Data: 3
Molecular Structure:
Molecular Structure of 1165-39-5 (AFLATOXIN G1)
Formula: C17H12O7
Molecular Weight: 328.278
Synonyms: 1H,12H-Furo[3',2':4,5]furo[2,3-h]pyrano[3,4-c][1]benzopyran-1,12-dione,3,4,7a,10a-tetrahydro-5-methoxy-, (7aR-cis)-;Aflatoxin G1 (7CI);
EINECS: 214-615-9
Density: 1.596 g/cm3
Melting Point: 244-246 °C
Boiling Point: 612.083 °C at 760 mmHg
Flash Point: 274.15 °C
Solubility: 15mg/L(temperature not stated)
Appearance: white crystalline powder
Hazard Symbols: VeryT+,FlammableF,HarmfulXn
Risk Codes: 45-26/27/28-65-48/23/24/25-36/38-11-46-39/23/24/25-23/24/25-36-20/21/22
Safety: 53-28-36/37-45-62-26-16-7-36
Transport Information: UN 3462 6
PSA: 84.20000
LogP: 1.86050
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Chemistry

Aflatoxin G1 is a mycotoxin, which may be produced by mold species of the genus Aspergillus in areas of the world with hot and humid climate.
Appearance: White to faint yellow powder
MF: C17H12O7
MW: 328.27
mp  244-246 °C 
Fp  -11 °C
storage temp.  2-8°C

Toxicity Data With Reference

1.   

mma-sat 31 ng/plate

   MUREAV    Mutation Research. 130 (1984),79.
2.   

cyt-mky:kdy 2 mg/L/2H-C

   JNCIAM    Journal of the National Cancer Institute. 48 (1972),1647.
3.   

ipr-rat LD50:14,900 μg/kg

   JPTLAS    Journal of Pathology. 102 (1970),209.
4.   

orl-dck LD50:785 μg/kg

   PSEBAA    Proceedings of the Society for Experimental Biology and Medicine. 123 (1966),151.

Consensus Reports

IARC Cancer Review: Animal Sufficient Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 10 (1976),p. 51.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) .

Safety Profile

Confirmed human carcinogen with experimental carcinogenic and neoplastigenic data. Poison by ingestion and intraperitoneal routes. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes. See also various aflatoxins.