CAS No.117467-28-4,Cefditoren pivoxil Suppliers

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Basic Information

Molecular Structure:
CAS No.:	117467-28-4
Name:	Cefditoren pivoxil
Article Data:	15

Formula:	C₂₅H₂₈N₆O₇S₃
Molecular Weight:	620.731
Synonyms:	5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[2-(4-methyl-5-thiazolyl)ethenyl]-8-oxo-,(2,2-dimethyl-1-oxopropoxy)methyl ester, [6R-[3(Z),6a,7b(Z)]]-;CCRIS 7768;Cefditorenpivaloyloxymethyl ester;Cefditoren pivoxyl;Cefditorin;ME1207;Meiact;Spectracef;
EINECS:	688-157-7
Density:	1.55 g/cm³
Melting Point:	207-209 °C
Solubility:	freely soluble in dilute hydrochloric acid and soluble at levels equal to 6.06 mg/mL in ethanol and <0.1 mg/mL in water.
Appearance:	off-white powder
PSA:	257.18000
LogP:	3.20810

Raw Materials

Total:161 Page 1 of 5 1 2 3 4 5 Next>>

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Chemistry

IUPAC Name: 2,2-Dimethylpropanoyloxymethyl (6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(Z)-2-(4-methyl-1,3-thiazol-5-yl)ethenyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Synonyms of Cefditoren pivoxil (CAS NO.117467-28-4): Cefditoren Pivoxil [JAN] ; Cefditoren pivaloyloxymethyl ester ; ME 1207 ; CCRIS 7768 ; Cefditoren PI voxil ; Cefditorin ; ME 1207 ; Spectracef ; UNII-78THA212DH ; 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-((1Z)-2-(4-methyl-5-thiazolyl)ethenyl)-8-oxo-,2,2-dimethyl-1-oxopropoxy)methyl ester, (6R,7R)- ; 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl)(methoxyimino)acetyl)amino)-3-(2-(4-methyl-5-thiazolyl)ethenyl)-8-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, (6R-(3(Z),6-alpha,7-beta-(Z)))-
CAS NO: 117467-28-4
Classification Code: Anti-Bacterial Agents ; Anti-Infective Agents ; Drug / Therapeutic Agent ; Reproductive Effect
Molecular Formula of Cefditoren pivoxil (CAS NO.117467-28-4): C₂₅H₂₈N₆O₇S₃
Molecular Weight: 620.7208
Molecular Structure:

Melting Point: 207-209°C
ProductCategories: Intermediates & Fine Chemicals ; Pharmaceuticals ; Sulfur & Selenium Compounds ; Cefditoren
H bond acceptors: 13
H bond donors: 3
Freely Rotating Bonds: 12
Polar Surface Area: 225.61 Å²
Index of Refraction: 1.71
Molar Refractivity: 156.27 cm³
Molar Volume: 399.7 cm³
Surface Tension: 63.1 dyne/cm
Density of Cefditoren pivoxil (CAS NO.117467-28-4): 1.55 g/cm³

Uses

Cefditoren pivoxil (CAS NO.117467-28-4) is used for an antibacterial. It is the third generation cephalosporin.

Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD	oral	> 2gm/kg (2000mg/kg)	KIDNEY, URETER, AND BLADDER: OTHER CHANGES	Chemotherapy Vol. 40(Suppl,
mouse	LD50	intraperitoneal	5gm/kg (5000mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Chemotherapy Vol. 40(Suppl,
mouse	LD50	oral	> 5100mg/kg (5100mg/kg)		Chemotherapy Vol. 40(Suppl,
mouse	LD50	subcutaneous	> 5gm/kg (5000mg/kg)		Chemotherapy Vol. 40(Suppl,
rat	LD50	oral	> 5100mg/kg (5100mg/kg)		Chemotherapy Vol. 40(Suppl,
rat	LD50	subcutaneous	> 5gm/kg (5000mg/kg)	SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE"	Chemotherapy Vol. 40(Suppl,
rat	LDLo	intraperitoneal	5gm/kg (5000mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Chemotherapy Vol. 40(Suppl,

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