Detail of "1177-87-3"

MSDS Download
CAS Number:
1177-87-3
Name:
Dexamethasone-17-acetate
Molecular Structure:
Formula:
C₂₄H₃₁FO₆
Molecular Weight:
434.55
Synonyms:
Dex-Cortideltacetate;Dexa-Cortisyl;Fortecortin;Fortecortin (crystal suspension);Pregna-1,4-diene-3,20-dione,21-(acetyloxy)-9-fluoro-11,17-dihydroxy-16-methyl-, (11b,16a)-;Pregna-1,4-diene-3,20-dione,9-fluoro-11b,17,21-trihydroxy-16a-methyl-, 21-acetate (6CI,8CI);16a-Methyl-9a-fluoroprednisolone 21-acetate;Dalalone DP;Dalalone LA;Decadron LA;Decadronal;Dectancyl;Dexamethasone acetate;
EINECS:
214-646-8
Density:
1.3 g/cm³
Melting Point:
238-240 ºC(lit.)
Boiling Point:
579.4 ºC at 760 mmHg
Flash Point:
304.2 ºC
Solubility:
5.47 mg/L at 25 ºC in water
Appearance:
White or almost white crystalline powder
Hazard Symbols:
Xi
Risk Codes:
43
Safety:
36/37 Details

Famous Chemical Enterprises

Livzon
Total
Shell
Dupont
Exxonmobil
Akzonobel
Basf
Bayer
BP

Other Products

All Suppliers

Supplier Location
Supplier Location
- China (Mainland)(26)
- Germany(2)
- Macao(2)
- Canada(1)
- India(1)
Business Type
Business Type
- Lab/Research institutions(2)
- Manufacturers(1)
- Trading Company(28)
Certificates
Certificates
- ISO(1)
- Production License (0)
Exhibitions
Exhibitions
- CPhI China

Please post your buying leads>>

Display：

Manufacturer
Enterprise Authentication
Suppiers of more reward points first
New supplier

Please post your buying leads,so that our qualified suppliers will soon contact you!
*Required Fields

Reference

Influence of steroids and stress on toxicity and disposition of tetraethylammonium bromide: Influence of steroids and stress on toxicity and disposition of tetraethylammonium bromide. Kourounakis, Panos; Selye, Hans (Inst. Med. Chir. Exp., Univ. Montreal, Montreal, Que., Can.There are some reagents with their cas registry numbers 124-94-7 and 71-91-0 are used in this study.). J. Pharm. Sci., 65(12), 1838-40 (English) 1976. CODEN: JPMSAE. DOCUMENT TYPE: Journal CA Section: 2 (Hormone Pharmacology) Section cross-reference(s): 4 In female rats, pretreatment with dexamethasone acetate (I acetate) [1177-87-3] or triamcinolone [124-94-7] decreased the toxicity and plasma concns. of tetraethylammonium bromide [71-91-0] while increasing its level in urine. Although starvation or restraint neither diminished the tetraethylammonium bromide concns. in plasma nor accelerated its urinary excretion, its toxicity was diminished by the stress induced with spinal cord lesions, heat, cold, hydrocortisone, or reserpine as well as starvation or restraint. Apparently, stress-induced resistance to tetraethylammonium bromide can not be attributed to elevated plasma corticosterone [50-22-6] levels, whereas gluccorticoid-induced resistance can be partially ascribed to increased urinary excretion of the toxicant. .

Inhibition of T cell-mediated cytotoxicity by anti-inflammatory steroids: Inhibition of T cell-mediated cytotoxicity by anti-inflammatory steroids. Schleimer, Robert P.; Jacques, Allen; Shin, Hyun S.; Lichtenstein, Lawrence M.; Plaut, Marshall (Sch. Med., Johns Hopkins Univ., Baltimore, MD 21239, USA). J. Immunol., 132(1), 266-71 (English) 1984. CODEN: JOIMA3. ISSN: 0022-1767. DOCUMENT TYPE: Journal CA Section: 2 (Mammalian Hormones) Section cross-reference(s): 15 Although acute exposure to glucocorticoids did not inhibit the activity of freshly obtained immune mouse splenic cytotoxic T-lymphocytes (CTL), preincubation of these CTL for several hours with subnanomolar concns. of several different glucocorticoids caused marked inhibition. The relative inhibitory potency of the steroids tested correlated with their reported activity both in glucocorticoid receptor binding assays and in assays of anti-inflammatory potency in man. The inhibitory effects of low concns. (10-10-10-9M) of dexamethasone acetate [1177-87-3] were reversed by human or mouse interleukin 2 (IL 2)-contg. supernatants, but were not reversed by IL 1-contg. supernatants. 50-23-7 and 10-10-1 which are cas registry numbers of substances are two of reagents here. The inhibitory effects of higher concns. (10-8-10-7M) of dexamethasone were not reversed even by very high doses of mouse IL 2. In contrast to previous reports of minimal direct glucocorticoid effects on CTL activity, the present results suggest that after preincubation, splenic CTL from in vivo-immune mice are sensitive to inhibition by glucocorticoids, and the glucocorticoids may act both indirectly (on IL 2 prodn.) and directly on the CTL. .

Detail of "1177-87-3"

Dexamethasone-17-acetate

Famous Chemical Enterprises

Related products

Other Products

Supplier Location

Business Type

Certificates

Exhibitions

CAS No.1177-87-3 Dexamethasone-17-acetate

CAS No.1177-87-3 Dexamethasone-17-acetate

CAS No.1177-87-3 Dexamethasone-17-acetate

CAS No.1177-87-3 Dexamethasone-17-acetate

CAS No.1177-87-3 Dexamethasone-17-acetate

CAS No.1177-87-3 Dexamethasone-17-acetate

CAS No.1177-87-3 Dexamethasone-17-acetate

CAS No.1177-87-3 Dexamethasone-17-acetate

CAS No.1177-87-3 Dexamethasone-17-acetate

CAS No.1177-87-3 Dexamethasone-17-acetate

CAS No.1177-87-3 Dexamethasone-17-acetate

CAS No.1177-87-3 Dexamethasone-17-acetate

CAS No.1177-87-3 Dexamethasone-17-acetate

CAS No.1177-87-3 Dexamethasone-17-acetate

CAS No.1177-87-3 Dexamethasone-17-acetate

CAS No.1177-87-3 Dexamethasone-17-acetate

CAS No.1177-87-3 Dexamethasone-17-acetate

CAS No.1177-87-3 Dexamethasone-17-acetate

CAS No.1177-87-3 Dexamethasone-17-acetate

CAS No.1177-87-3 Dexamethasone-17-acetate

CAS No.1177-87-3 Dexamethasone-17-acetate

CAS No.1177-87-3 Dexamethasone-17-acetate

CAS No.1177-87-3 Dexamethasone-17-acetate

CAS No.1177-87-3 Dexamethasone-17-acetate

CAS No.1177-87-3 Dexamethasone-17-acetate

CAS No.1177-87-3 Dexamethasone-17-acetate

CAS No.1177-87-3 Dexamethasone-17-acetate

CAS No.1177-87-3 Dexamethasone-17-acetate

CAS No.1177-87-3 Dexamethasone-17-acetate

CAS No.1177-87-3 Dexamethasone-17-acetate

CAS No.1177-87-3 Dexamethasone-17-acetate

CAS No.1177-87-3 Dexamethasone-17-acetate

Reference