Reference

Persistent efficacy of abamectin and doramectin against gastrointestinal nematodes of cattle

Persistent efficacy of abamectin and doramectin against gastrointestinal nematodes of cattle. Rolfe, P.F.; Dawson, K. L.; Soll, M.D.; Nichols, G. K.; Ryan, W. G. ( NSW Agriculture, Elizabeth Macarthur Agricultural Institute, Camden, Australia). Australian Veterinary Journal, 75(1), 33-35 (English) 1997 Australian Veterinary Association. CODEN: AUVJA2. ISSN: 0005-0423. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) We assessed the persistent activity of injectable formulations of abamectin and doramectin against gastro-intestinal nematodes of cattle. Nematode-free calves were treated with abamectin or doramectin (each at a dose of 200 mg/kg) and infections then induced with repeated doses of infective larvae of Trichostrongylus axei, Haemonchus placei, Ostertagia ostertagi and Cooperia species. The duration of challenge ranged from 14 to 28 days. The calves were slaughtered at either 38/39 or 45/46 days after the treatments and nematodes recovered from the gastro-intestinal tract. Significant redns. in nos. of O. ostertagi occurred for both abamectin and doramectin treatments (> 93%) relative to counts in untreated calves, when challenge was administered up to 21 days after treatment. 71751-41-2 and 117704-25-3 which are cas registry numbers of chemicals are mentioned. For T. axei and Cooperia species, significant redns. occurred when the challenge occurred 14 days after treatment (99%). Although differences from untreated animals were not significant, the results for H. placei suggested high efficacy (> 85%) for up to 21 days for doramectin and up to 28 days for abamectin. There was no significant difference between abamectin and doramectin for any parasite at any challenge point, indicating that there is equiv. persistent activity of doramectin and abamectin against important gastrointestinal nematodes of cattle. .

Efficacy of doramectin in ecto-endo-parasitic infestation in goats

Efficacy of doramectin in ecto-endo-parasitic infestation in goats. Gupta, Vinod K.; Kumar, Ashok; Arora, N.; Vihan, V. S. (Central Institute for Research on Goats, Mathura 281122, India). Indian Veterinary Medical Journal, 27(1), 81-82 (English) 2003 U. P. Veterinary Association. CODEN: IVMJDL. ISSN: 0250-5266. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) This study suggested that doramectin is a safe and effective alternative acaricidal drug to avoid dipping stress in winter season. Doramectin injection was administered in non-lactating goats belonging to Barbari and Jamunapari breed of both sex (518) in strategic deworming. Drug efficacy was assessed by monitoring the EPG load. It was obsd. that av.In this experiment, several chemicals are used like 117704-25-3 EPG 1650 (Range - 600-2600) was decreased to the level of 200 in all the cases. .