Reference

Spectrophotometric studies of some heterocyclic amino esters of 3,4,5-trimethoxybenzoic acid

Spectrophotometric studies of some heterocyclic amino esters of 3,4,5-trimethoxybenzoic acid.Some chemicals with cas registry numbers like 42013-42-3 and 42013-41-2 are also used. Reizniece, H.; Petersone, B.; Zilishke, A. P.; Sauka, J.; Auzina, D. (USSR). Nauka - Prakt. Farm., 176-9. Edited by: Petersone, E. Yu. Rizh. Med. Inst.: Riga, USSR. (Russian) 1974. CODEN: 34KFAY. DOCUMENT TYPE: Conference CA Section: 64 (Pharmaceutical Analysis) Section cross-reference(s): 73 The UV absorption spectra (max. at 265 nm) were detd. for 5 piperidino-, pyrrolidino-, and morpholinoethyl- esters of 3,4,5-trimethoxybenzoic acid [118-41-2]. All spectra conformed to Beer's Law. The specific absorption index (E1cm1%) was calcd. for each ester and calibration curves were constructed for use in subsequent quant. detns. .

Weak electrolyte transfer in the guinea pig jejunum: secretion of trimethoxybenzoic acid

Weak electrolyte transfer in the guinea pig jejunum: secretion of trimethoxybenzoic acid. Kolassa, N.; Krivanek, P.; Turnheim, K. (Pharmakol. Inst., Univ. Wien, Vienna, Austria). Naunyn-Schmiedeberg's Arch. Pharmacol., 298(3), 223-8 (English) 1977. CODEN: NSAPCC. DOCUMENT TYPE: Journal CA Section: 3 (Biochemical Interactions) Section cross-reference(s): 1 In isolated epithelia of guinea pig jejunum the transcellular permeation of 10-4M 14C-labeled 3,4,5-trimethoxybenzoic acid (I) [118-41-2] in the direction blood-lumen was 10 times greater than the transcellular permeation of 10-4M I from the lumen to the blood. Under aerobic conditions the cellular uptake of I (10-4M) from the blood side was twice as high as that from the lumen side. In anaerobiosis the percentage of I taken up into the epithelium was enhanced when I was administered on the lumen side, whereas the percentage was unchanged after administration on the blood side. Similar results were obtained under aerobic conditions, whenever the I concn. was increased up to 10-2M. The results are consistent with a 3-compartment model with an intermediate compartment distinguished by a high pH as compared to that of the outer compartments and by a luminal boundary highly permeable for the ionized form of the substrate in contrast to the contraluminal boundary.