Reference

Use of dl-norephedrine hydrochloride

Use of dl-norephedrine hydrochloride. Trenker, Ady (Belg. ). Belg. BE 898851 A1 30 May 1984,13 pp. (French). (Belgium). CODEN: BEXXAL. ICI: A61. APPLICATION: BE 21-346 7 Feb 1984. DOCUMENT TYPE: Patent CA Section: 63 (Pharmaceuticals) Section cross-reference(s): 1, 25 dl-Norephedrine-HCl (I) [154-41-6], in addn. to possessing sympathomimetic activity, is also useful as an anorexigenic agent and may be used in tablets, suspensions, capsules, etc. Thus, I was prepd. by the hydrogenation of isonitrosopropiophenone [119-51-7] in MeOH-HCl soln. I administered 25 mg 3 times a day 30 min before meal was well tolerated by humans. I produced a significant loss in wt. after 4 wk treatment.

Aromatic oximes

Aromatic oximes. Koenders, Peter; Kok, Riekert; Van der Zeeuw, Abraham Johannes (Shell Internationale Research Maatschappij B. V., Neth.). Pat. Specif. (Aust.) AU 529791 B2 23 Jun 1983, 17 pp. (English). (Australia).Several reagents with their cas registry numbers 89422-01-5 and 119-51-7 are used here. CODEN: ALXXAP. CLASS: IC: C07C131-00. APPLICATION: AU 81-67988 2 Mar 1981. DOCUMENT TYPE: Patent CA Section: 25 (Benzene, Its Derivatives, and Condensed Benzenoid Compounds) Diketone oximes I [R = H, (un)substituted hydrocarbyl; R1 = (un)substituted alkyl; R2 = R3 = H, R2R3 = CH:CHCH:CH; X = O, NOH] were prepd. Thus, 1-dodecylnaphthalene underwent Friedel-Crafts acylation with EtCOCl to give 95% 1-(4-dodecyl-1-naphthalenyl)-1-propanone. This was treated with HCl and Me2CHONO2 to give 82% I (R = dodecyl, R1 = Me, R2R3 = CH:CHCH:CH, X = O). This was treated with H2NOH.HCl to give quant. anti-I (R = dodecyl, R1 = Me, R2R3 = CH:CHCH:CH, X = NOH). I are useful for liq.-liq. extn. of Cu (no data). .