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119413-54-6

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Basic Information
CAS No.: 119413-54-6
Name: Topotecan hydrochloride
Article Data: 10
Molecular Structure:
Molecular Structure of 119413-54-6 (Topotecan hydrochloride)
Formula: C23H23N3O5.HCl
Molecular Weight: 457.914
Synonyms: Topotecan HCl;Hycamtin;NSC 609669;Nogitecan hydrochloride;SKF 104864A;SKFS 104864A;
EINECS: 601-607-9
Density: 1.49 g/cm3
Melting Point: 213-218 °C
Boiling Point: 782.9 °C at 760 mmHg
Flash Point: 427.3 °C
Appearance: White Crystalline Solid
Hazard Symbols: ToxicT
Risk Codes: 25-36/37/38-46
Safety: 26-36/37/39-45
PSA: 104.89000
LogP: 2.64880
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  • Casno:

    119413-54-6

    Topotecanhydrochloride

    Min.Order: 1 Milligram

    FOB Price:  USD $ 0.0-0.0

    GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

  •  Xiamen Jenny Chemical Technology Co., Ltd.

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:+86

    Address:xiameng

       Inquiry Now

  • Topotecan hydrochloride

  • Casno:

    119413-54-6

    Topotecan hydrochloride

    Min.Order: 1 Kilogram

    FOB Price:  USD $ 18.0-20.0

    factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

    Founded in 2008, East Chemsources Limited is a professional manufacturer of supplier in food and beverage, pharmaceuticals, cosmetics and other industries. pharmaceutical field in

  •  EAST CHEMSOURCES LIMITED

     China (Mainland)  |  Contact Details

    Business Type:Trading Company

    Tel:15053231572

    Address:No.1581-12,Jinshui Road, Licang, Qingdao,China

       Inquiry Now

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Chemistry

The Molecular formula of  Topotecan HCl (119413-54-6): C23H24ClN3O5
The Molecular Weight of  Topotecan HCl (119413-54-6): 457.91
Molecular Structure : 
Melting point:  213-218 °C 
Index of Refraction: 1.733
Surface Tension: 82.8 dyne/cm
Density: 1.49 g/cm3
Flash Point: 427.3 °C
Enthalpy of Vaporization: 119.49 kJ/mol
Boiling Point: 782.9 °C at 760 mmHg
Vapour Pressure: 8.13E-26 mmHg at 25 °C 
Appearance of Topotecan HCl (119413-54-6): White Crystalline Solid

 

Uses

 Topotecan HCl (119413-54-6) is naturally occurring amino acid.It is the precursor of tetrapyrroles in the biosynthesis of chlorophyll and heme.And it is antineoplastic (photosensitizer),especially a DNA topoisomerase I inhibitor,just like semisynthetic analog of Camptothecin.

Safety Profile

The Hazard Codes of  Topotecan HCl (119413-54-6) :  T
The Risk Statements information of  Topotecan HCl (119413-54-6): 25-36/37/38-46
25:  Toxic if swallowed 
46:  May cause heritable genetic damage
36/37/38:  Irritating to eyes, respiratory system and skin
The Safety Statements information of  Topotecan HCl (119413-54-6): 26-36/37/39-45
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice    
45:  In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) 
36/37/39:  Wear suitable protective clothing, gloves and eye/face protection 

Specification

 Topotecan HCl (119413-54-6),also called topotecan monohydrochloride;topetecan hydrochloride;5-piperazin-1-yl-benzofuran-2-carboxylic acid ethyl ester,is white crystalline solid.