Reference

Spectrophotometric determination of some water-soluble vitamins in pharmaceutical preparations

Spectrophotometric determination of some water-soluble vitamins in pharmaceutical preparations. Moussa, Abd El-Fattah A.; Hassan, S. M. (Drug Anal. Dep.Chemicals with cas numbers 12001-77-3 and 62201-22-3 also play role., Cent. Med. Lab. Armed Forces, Cairo, Egypt). Pharmazie, 32(1), 50-1 (English) 1977. CODEN: PHARAT. DOCUMENT TYPE: Journal CA Section: 64 (Pharmaceutical Analysis) Thiamin [59-43-8] and pyridoxine [65-23-6] were detd. simultaneously in pharmaceutical prepns. by UV spectrophotometry. Pyridoxine was detd. directly by measuring its absorbane at 325 nm in glycerinated phosphate buffer of pH 7. Thiamin was detd. by measuring its absorbance at 268 nm with pyridoxine interference eliminated by the correction factor of 0.211 and riboflavin [83-88-5] interference eliminated by multiplying its absorbance at 446 nm by the correction factor of 2.61. Thiamin and pyridoxine were detd. in Bedoxin [12001-77-3] tablets and Trivarol [62201-22-3] and Tetraviton [37304-89-5] injections with mean recoveries of 100.51 and 100.08%, resp. .