Reference

The ability of fipronil to prevent transmission of Borrelia burgdorferi, the causative agent of lyme disease to dogs

The ability of fipronil to prevent transmission of Borrelia burgdorferi, the causative agent of lyme disease to dogs. Jacobson, Richard; McCall, John; Hunter, James, III; Alva, Roberto; Irwin, Jennifer; Eschner, Andrew; Jeannin, Philippe; Boeckh, Albert ( College of Veterinary Medicine, Cornell University, USA). Journal of Applied Research in Veterinary Medicine, 2(1), 39-45 (English) 2004 Veterinary Solutions LLC. CODEN: JARVAB. ISSN: 1542-2666. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) Objective: To assess the efficacy of fipronil spray and fipronil/(S)-methoprene spot-on against Ixodes scapularis and in preventing tick transmission of Borrelia burgdorferi. Design: Two parallel, blinded randomized, controlled studies. Animals: Forty-eight beagle dogs. Procedure: Dogs were matched by body wt. and randomly allocated, 8 per group, to untreated controls or to treatment with fipronil spray (2 groups) or fipronil/(S)-methoprene spot on (2 groups), applied either 7 or 28 days before challenge with B. burgdorferi-infected ticks. Tick counts were conducted 48 and 120 h after challenge. Assessment of successful B. burgdorferi transmission was performed using serol. and skin biopsies from tick attachment sites for culture and polymerase chain reaction assay. Results: I. scapularis infestation and B. burgdorferi transmission was successful in all control dogs. Fipronil spray prevented all dogs from becoming infected with B. burgdorferi and was 100% and 99.6% effective against tick infestation 48 h after challenge in dogs treated 7 or 28 days before challenge. When challenge occurred 7 days after treatment, fipronil/(S)-methoprene spot on was 100% effective against the tick infestation 48 h after challenge and prevented infection with B. burgdorferi in all dogs.In this experiment, several chemicals are used like 120068-37-3 and 741709-55-7 When the challenge was conducted 28 days after treatment, fipronil/(S)-methoprene spot on prevented all but 2 dogs from becoming infected with B. burgdorferi and was 97.6% effective against tick infestation 48 h after challenge. .

Gel-like insecticidal composition to control cockroaches

Gel-like insecticidal composition to control cockroaches. Shestakov, K. A.; Levi, M. I.; Kreingol'd, S. U.; Rasnitsyn, S. P.; Avrutskii, M. M. (GUP "Moskovskii Gorodskoi Tsentr Dezinfektsii" MGTsD, Russia). Russ. RU 2245036 C2 27 Jan 2005, No pp. given (Russian). (Russia). CODEN: RUXXE7. CLASS: ICM: A01N025-04. ICS: A01N025-28. APPLICATION: RU 2001-129524 2 Nov 2001. DOCUMENT TYPE: Patent CA Section: 5 (Agrochemical Bioregulators) Section cross-reference(s): 12 The invention provides a gel-like insecticidal compn., in particular to control cockroaches. 9004-53-9 and 120068-37-3 are just another two chemicals used in this study. The insecticidal gel of the invention contains lipid-microencapsulated different types of insecticides with functional additives. The insecticide is highly efficient and has a prolonged residual effect. .