CAS No.120116-88-3,CYAZOFAMID Suppliers

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Basic Information

CAS No.:

120116-88-3

Name:

CYAZOFAMID

Article Data:

Molecular Structure:

Formula:

C13H13 Cl N4 O2 S

Molecular Weight:

324.791

Synonyms:

(4-Chloro-2-cyano-N,N-dimethyl-5-p-tolylimidazole-1-sulfonamide);BAS 54500F; Cyamidazosulfamid; Cyazofamid; Docious; Fendazosulam; IKF 916;Mildicut; Ranman

Density:

1.38g/cm³

Melting Point:

152.7°

Boiling Point:

498.2°Cat760mmHg

Flash Point:

255.1°C

Hazard Symbols:

Risk Codes:

11-38-48/20-63-65-67-20/21/22

Safety:

Hazard Codes	F,Xn
Risk Statements	11-38-48/20-63-65-67-20/21/22
Safety Statements	36/37-62-36
RIDADR	UN1294 3/PG 2

PSA:

87.37000

LogP:

3.11888

Synthetic route

: 120118-14-1
5-chloro-4-(4-methylphenyl)-1H-imidazole-2-carbonitrile

: 13360-57-1
dimethylamino sulfonyl chloride

: 120116-88-3
4-chloro-2-cyano-N,N-dimethyl-5-(4-methylphenyl)-1H-imidazole-1-sulfonamide

Conditions

Conditions	Yield
With potassium carbonate In ethyl acetate for 3h; Reflux;	96.2%
With potassium carbonate In ethyl acetate for 6h; Solvent; Reflux;	94%
With potassium carbonate In cyclohexane; ethyl acetate Concentration; Solvent; Reflux;	86%
With potassium carbonate In ethyl acetate Reflux;
With potassium carbonate In ethyl acetate at 75℃; for 10.5h;	68 g

: C13H14N4O2S

: 120116-88-3
4-chloro-2-cyano-N,N-dimethyl-5-(4-methylphenyl)-1H-imidazole-1-sulfonamide

Conditions

Conditions	Yield
With N-chloro-succinimide In acetonitrile at 20℃; for 4h; Time;	95%

: 5-(4'-methylphenyl)imidazole-2-carboxylic acid

: 120116-88-3
4-chloro-2-cyano-N,N-dimethyl-5-(4-methylphenyl)-1H-imidazole-1-sulfonamide

Conditions

Conditions	Yield
Multi-step reaction with 5 steps 1: thionyl chloride / 5 h / 85 °C / Cooling with ice 2: ammonia / methanol / 36 h / 0 °C 3: thionyl chloride / 12 h / 85 °C 4: N-chloro-succinimide / acetonitrile / 3 h / 25 °C 5: potassium carbonate / ethyl acetate / 6 h / Reflux View Scheme

: 5-(4'-methylphenyl)imidazole-2-carboxylic acid ethyl ester

: 120116-88-3
4-chloro-2-cyano-N,N-dimethyl-5-(4-methylphenyl)-1H-imidazole-1-sulfonamide

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: ammonia / methanol / 36 h / 0 °C 2: thionyl chloride / 12 h / 85 °C 3: N-chloro-succinimide / acetonitrile / 3 h / 25 °C 4: potassium carbonate / ethyl acetate / 6 h / Reflux View Scheme

: C11H11N3O

: 120116-88-3
4-chloro-2-cyano-N,N-dimethyl-5-(4-methylphenyl)-1H-imidazole-1-sulfonamide

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: thionyl chloride / 12 h / 85 °C 2: N-chloro-succinimide / acetonitrile / 3 h / 25 °C 3: potassium carbonate / ethyl acetate / 6 h / Reflux View Scheme

: 122-00-9
para-methylacetophenone

: 120116-88-3
4-chloro-2-cyano-N,N-dimethyl-5-(4-methylphenyl)-1H-imidazole-1-sulfonamide

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1: selenium(IV) oxide / 1,4-dioxane; water / 5 h / 50 - 110 °C 2: hydroxylamine hydrochloride / water; methanol / 2 h / Reflux 3: thionyl chloride / ethyl acetate / 3 h / Reflux 4: potassium carbonate / ethyl acetate / 3 h / Reflux View Scheme
Multi-step reaction with 4 steps 1.1: acetic acid; bromine / 7 h / 42 °C 2.1: hydroxylamine / methanol / 12 h / 50 °C 3.1: ammonia / methanol / 32 h / 0 °C 3.2: 10 h / 88 °C 3.3: 2.5 h / 28 °C 4.1: potassium carbonate / ethyl acetate / Reflux View Scheme

: 1075-47-4
4-methylphenylglyoxal

: 120116-88-3
4-chloro-2-cyano-N,N-dimethyl-5-(4-methylphenyl)-1H-imidazole-1-sulfonamide

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: hydroxylamine hydrochloride / water; methanol / 2 h / Reflux 2: thionyl chloride / ethyl acetate / 3 h / Reflux 3: potassium carbonate / ethyl acetate / 3 h / Reflux View Scheme

: 13664-98-7
2,2-dibromo-1-(4-methylphenyl)ethanone

: 120116-88-3
4-chloro-2-cyano-N,N-dimethyl-5-(4-methylphenyl)-1H-imidazole-1-sulfonamide

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1.1: hydroxylamine / methanol / 12 h / 50 °C 2.1: ammonia / methanol / 32 h / 0 °C 2.2: 10 h / 88 °C 2.3: 2.5 h / 28 °C 3.1: potassium carbonate / ethyl acetate / Reflux View Scheme

: 1-hydroxy-4-(4-methylphenyl)-3-oxide-1H-imidazole-2-carboxaldehyde oxime

: 120116-88-3
4-chloro-2-cyano-N,N-dimethyl-5-(4-methylphenyl)-1H-imidazole-1-sulfonamide

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: sodium metabisulfite / N,N-dimethyl acetamide; acetonitrile / 4 h / 80 - 105 °C 2: sulfuryl dichloride / N,N-dimethyl acetamide; acetonitrile / 20 - 25 °C 3: potassium carbonate / ethyl acetate / 10.5 h / 75 °C View Scheme

: 670-91-7
4(5)-(4-tolyl)-1H-imidazole

: 120116-88-3
4-chloro-2-cyano-N,N-dimethyl-5-(4-methylphenyl)-1H-imidazole-1-sulfonamide

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1: potassium carbonate / ethyl acetate / 6 h / 77 °C 2: copper(l) iodide; dipotassium peroxodisulfate / N,N-dimethyl-formamide / 12 h / 110 °C 3: N-chloro-succinimide / acetonitrile / 4 h / 20 °C View Scheme