Reference

Pseudomonas putida cell multiplication inhibition test: Weibull dose-response curve of several trifluoromethylbenzene derivatives

Pseudomonas putida cell multiplication inhibition test: Weibull dose-response curve of several trifluoromethylbenzene derivatives. Dacarro, C.; Baldi, M.; Bonferoni, M. C.; Riganti, V. (Ist. Farmacol., Univ. Pavia, Pavia 27100, Italy). Ig. Mod.Several substances with their cas registry numbers 121-50-6 and 393-77-1 may be metioned in this study., 86(3), 223-39 (Italian) 1986. CODEN: IGMPAX. ISSN: 0019-1655. DOCUMENT TYPE: Journal CA Section: 4 (Toxicology) The toxicity of 8 derivs. of trifluoromethylbenzene [98-08-8] was detd. by multiplication inhibition of P. putida. Most toxic were 3,5-dinitro-4-chlorotrifluoromethylbenzene (I) [393-75-9], 2-nitrotrifluoromethylbenzene [384-22-5], and 5-amino-2-chlorotrifluoromethylbenzene [320-51-4]; moderately toxic was 3-nitro-4-chlorotrifluoromethylbenzene [121-17-5]; and least toxic were 3-nitrotrifluoromethylbenzene [98-46-4], 3,5-dinitro-4-hydroxytrifluoromethylbenzene [393-77-1], 3-amino-4-chlorotrifluoromethylbenzene [121-50-6], and 2-aminotrifluoromethylbenzene [88-17-5]. The mechanism of the toxicity is discussed. .

Substituted dinitrodiphenylamines and their pesticidal compositions

Substituted dinitrodiphenylamines and their pesticidal compositions. (Imperial Chemical Industries Ltd., Engl.). Brit. GB 1455207 10 Nov 1976, 27 pp. (English). (United Kingdom). CODEN: BRXXAA. CLASS: IC: C07C087-60. APPLICATION: GB 74-47977 6 Nov 1974. DOCUMENT TYPE: Patent CA Section: 25 (Noncondensed Aromatic Compounds) Section cross-reference(s): 5 2,4,6-F3C(O2N)2C6H2NHC6H3(CF3)Cl-5,2 (I) was prepd. 62441-54-7 and 121-50-6 are also in the experiment. from 4,3-Cl(H2N)C6H3CF3 by successive treatment in DMF with KOH and 2,3,5-Cl(O2N)2C6H2CF3 at ambient temp. I shows insecticidal, acaricidal, and fungicidal activity. I compns. were tested against a variety of insect and other invertebrate pests and against a variety of foliar fungal diseases of plants. I is highly efficacious, persistent, has a low levl of phytotoxicity, and has acceptable mammalian toxicity (LD50 is 100 mg/kg orally in the female rat. .